Fortfahren mit
B5057
7-Benzyloxy-4-trifluoromethylcoumarin
≥99% (HPLC), solid
Synonym(e):
7-BFC
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Über diesen Artikel
Empirische Formel (Hill-System):
C17H11F3O3
Molekulargewicht:
320.26
UNSPSC Code:
12161501
PubChem Substance ID:
NACRES:
NA.47
MDL number:
Produktname
7-Benzyloxy-4-trifluoromethylcoumarin, ≥99% (HPLC), solid
Quality Level
assay
≥99% (HPLC)
form
solid
storage temp.
−20°C
SMILES string
FC(F)(F)C1=CC(=O)Oc2cc(OCc3ccccc3)ccc12
InChI
1S/C17H11F3O3/c18-17(19,20)14-9-16(21)23-15-8-12(6-7-13(14)15)22-10-11-4-2-1-3-5-11/h1-9H,10H2
InChI key
WVKLERKKJXUPIK-UHFFFAOYSA-N
Gene Information
rat ... Maoa(29253), Maob(25750)
Application
7-Benzyloxy-4-trifluoromethylcoumarin has been used:
- in the SBAD2-3x-AAGLY hepatocyte-like cell (HLC) functional assay to measure the cytochrome P450 3A4 (CYP3A4)-dependent activity
- in O-dealkylation reaction to determine the activity of CYP3A
- to measure the activity of CYP3A-mediated 7-benzyloxy-4-trifluoromethylcoumarin O-debenzylase activity (BFCOD)
Biochem/physiol Actions
Metabolized primarily by cytochrome P450 isozymes CYP1A2 and CYP3A4.
Legal Information
Supplied by Gentest Corp., U.S. Patent Nos. 6,207,404.
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Dieser Artikel | |||
|---|---|---|---|
| assay ≥99% (HPLC) | assay ≥95% (HPLC) | assay ≥90% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| form solid | form solid | form powder | form solid |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
| Gene Information rat ... Maoa(29253), Maob(25750) | Gene Information - | Gene Information human ... CASP3(836) | Gene Information - |
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
Lagerklasse
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
dust mask type N95 (US), Eyeshields, Gloves
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Global Trade Item Number
| SKU | GTIN |
|---|---|
| B5057-5MG | 04061833433577 |