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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
5 mg | Warenkorb auf Verfügbarkeit prüfen | € 147,00 |
25 mg | Warenkorb auf Verfügbarkeit prüfen | € 579,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C13H9Cl2N5·HCl · xH2O
CAS-Nummer:
Molekulargewicht:
342.61 (anhydrous basis)
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
Technischer Dienst
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Unterstützung erhaltenProduktname
A-438079 hydrochloride hydrate, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: 20 mg/mL, clear
originator
Abbott
storage temp.
2-8°C
SMILES string
O.Cl.Clc1cccc(c1Cl)-c2nnnn2Cc3cccnc3
InChI
1S/C13H9Cl2N5.ClH.H2O/c14-11-5-1-4-10(12(11)15)13-17-18-19-20(13)8-9-3-2-6-16-7-9;;/h1-7H,8H2;1H;1H2
InChI key
ZHFJJBAKSROKNO-UHFFFAOYSA-N
Application
A-438079 hydrochloride hydrate has been used to determine its inhibitory effect on purinergic receptors. It has also been used to check its inhibitory effects on macrophages.
Biochem/physiol Actions
A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist
A-438079 hydrochloride hydrate is a selective P2X7 purinoceptor antagonist in both human and rat with minimal activity at 75 different G-protein-coupled receptors, enzymes, transporters, and ion channels tested.
Features and Benefits
This compound was developed by Abbott. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
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Dieser Artikel | |||
|---|---|---|---|
| form powder | form powder | form - | form powder |
| assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) | assay ≥98% (HPLC) |
| Quality Level 100 | Quality Level 100 | Quality Level 100 | Quality Level 100 |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| storage condition desiccated | storage condition - | storage condition desiccated | storage condition - |
| solubility DMSO: 20 mg/mL, clear | solubility H2O: ≥10 mg/mL | solubility H2O: 30 mg/mL, clear | solubility DMSO: 2 mg/mL, clear (warmed) |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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