The solubility information can be found on the Specification sheet: Solubility (Solvent) Water or 1% Acetic Acid Solubility (Conc) 1.00 - 1.04 mg/ml. Stock solutions are stable for up to 3 months at -20°C.
Fortfahren mit
A1439
Pituitary adenylate cyclase activating polypeptide-38
Synonym(e):
PACAP-38
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
0.1 mg | Warenkorb auf Verfügbarkeit prüfen | € 333,00 |
Über diesen Artikel
Empirische Formel (Hill-System):
C203H331N63O53S
CAS-Nummer:
Molekulargewicht:
4534.26
UNSPSC Code:
41106305
NACRES:
NA.32
MDL number:
Form:
powder
Technischer Dienst
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Unterstützung erhaltenform
powder
Quality Segment
composition
Peptide content, ~70%
UniProt accession no.
storage temp.
−20°C
Gene Information
human ... ADCYAP1(116)
General description
Pituitary adenylate cyclase activating polypeptide-38 (PACAP38) is mapped to human chromosome 18. 27-residue-amidated fragment (PACAP27) comprises another isoform. The PACAP38 is major isoform associated with mammals.[1]
Application
Biochem/physiol Actions
PACAP-38 is a neuropeptide that has substantial sequence homology to vasoactive intestinal peptide (VIP). It is reported to serve as a neuronal survival factor.
Pituitary adenylate cyclase activating polypeptide-38 (PACAP38) is a cardioprotectant and may help in treating radiation-induced heart disease (RIHD). It plays a protective role during oxidative stress in cardiomyocytes. PACAP38 has antioxidant, anti-apoptotic and anti-inflammatory property.[4] It is implicated in the pathophysiology of migraine and cluster headache.[5]
Other Notes
Lyophilized from 0.1% TFA in H2O
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| form powder | form solid | form lyophilized powder | form lyophilized powder |
| Quality Level 200 | Quality Level 100 | Quality Level 200 | Quality Level 200 |
| storage temp. −20°C | storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C |
| Gene Information human ... ADCYAP1(116) | Gene Information - | Gene Information bovine ... FGF2(281161) | Gene Information - |
| composition Peptide content, ~70% | composition - | composition - | composition - |
| UniProt accession no. | UniProt accession no. - | UniProt accession no. | UniProt accession no. - |
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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How can stock solutions for item A1439, Pituitary adenylate cyclase activating polypeptide-38, be reconstituted and stored?
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