72715

Glutaryl-L-carnitin Lithiumsalz

≥98.0% (TLC)

• Synonym(e): L-Carnitine lithium glutarate
• Empirische Formel (Hill-System): C₁₂H₂₁NO₆ · xLi⁺
• CAS-Nummer: 102636-82-8
• Molekulargewicht: 275.30 (free acid basis)
• UNSPSC Code: 41116107
• PubChem Substance ID: 329764299
• NACRES: NA.25

Eigenschaften

• Produktname: Glutaryl-L-carnitin Lithiumsalz, ≥98.0% (TLC)
• Quality Segment: 100
• assay: ≥98.0% (TLC)
• form: solid
• optical activity: [α]/D -20±2°, c = 1 in H₂O
• impurities: ≤10% water
• color: white to off-white
• storage temp.: 2-8°C
• SMILES string: C[N+](C)(C)C[C@H](OC(CCCC(O)=O)=O)CC([O-])=O.C
• InChI: 1S/C12H21NO6/c1-13(2,3)8-9(7-11(16)17)19-12(18)6-4-5-10(14)15/h9H,4-8H2,1-3H3,(H-,14,15,16,17)/t9-/m1/s1
• InChI key: NXJAXUYOQLTISD-SECBINFHSA-N

Beschreibung

Biochem/physiol Actions

Increased formation and excretion of glutarylcarnitin results from a glutaryl-CoA dehydrogenase deficiency, an inborn error of lysine and tryptophan metabolism. Secondary carnitine depletion due to increased formation and urinary excretion of glutarylcarnitine is suggested to play an important role in the neuropathogenesis of glutaryl-CoA dehydrogenase deficiency, inducing excitotoxic neuronal damage and mitochondrial dysfunction.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable