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50847

Gramicidin C aus Bacillus brevis

~90% (HPLC)

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Über diesen Artikel

CAS-Nummer:
MDL number:
UNSPSC Code:
51283112
NACRES:
NA.85
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biological source

Bacillus brevis

Quality Level

assay

~90% (HPLC)

form

powder

impurities

≤5% water

color

white to off-white

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

mode of action

cell membrane | interferes, enzyme | inhibits

storage temp.

2-8°C

SMILES string

CC(C)C[C@@H]1NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCN)NC(=O)[C@@H](NC(=O)[C@@H]4CCCN4C(=O)[C@@H](Cc5ccccc5)NC1=O)C(C)C)C(C)C

InChI key

IUAYMJGZBVDSGL-JYFSIOBESA-N

General description

Chemical structure: peptide

Application

Gramicidin is a naturally occuring polypeptide antibiotic. It functions as a transmembrane ion channel and is used for studies on phospholipid bilayer membrane fluidity measured by lateral diffusion.

Biochem/physiol Actions

Naturally occuring polypeptide antibiotic with Tyr at position 11; functions as a transmembrane ion channel.
Gramicidin′s bactericidal activity is a result of increasing the permeability of the bacterial cell membrane. This allows inorganic monovalent cations to travel through unrestricted which thereby destroys the ion gradient between the cytoplasm and the extracellular environment .

Packaging

10mg

Other Notes

Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place. Keep in a dry place.

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Dieser Artikel
11702B012550845
mode of action

cell membrane | interferes, enzyme | inhibits

mode of action

cell wall synthesis | interferes

mode of action

cell wall synthesis | interferes

mode of action

cell membrane | interferes, enzyme | inhibits

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

antibiotic activity spectrum

Gram-positive bacteria

antibiotic activity spectrum

Gram-positive bacteria

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria

Quality Level

100

Quality Level

200

Quality Level

200

Quality Level

100

form

powder

form

powder

form

powder

form

powder

assay

~90% (HPLC)

assay

-

assay

-

assay

-

biological source

Bacillus brevis

biological source

Bacillus licheniformis

biological source

Bacillus licheniformis

biological source

Bacillus brevis


Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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G.A. Brewer
Anal. Profiles Drug Subst., 8, 179-179 (1979)
Physiology and Pathology of Chloride Transporters and Channels in the Nervous System: From Molecules to Diseases.
Francisco J. Alvarez-Leefmans; Eric Delpire
Physiology and Pathology of Chloride Transporters and Channels in the Nervous System: From Molecules to Diseases, 142-142 (2009)
Dong Hyeon Lee et al.
Yonsei medical journal, 49(3), 459-471 (2008-06-27)
This study examined the expression and function of inward rectifier K(+) channels in cultured rat hepatic stellate cells (HSC). The expression of inward rectifier K(+) channels was measured using real-time RT-PCR, and electrophysiological properties were determined using the gramicidin-perforated patch-clamp



Global Trade Item Number

SKUGTIN
50847-10MG04061833267950

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