490M-1

Tyrosine Hydroxylase (LNC1) Mouse Monoclonal Antibody

• Synonym(e): TYH
• UNSPSC Code: 41116161
• Conjugate: unconjugated
• Clone: LNC1
• Application: IHC
• Citations: 4

Eigenschaften

• biological source: (Mouse)
• Quality Level: 500
• conjugate: unconjugated
• antibody form: (IgG1 Supernatant)
• antibody product type: primary antibodies
• clone: LNC1
• description: For In Vitro Diagnostic Use in Select Regions
• form: buffered aqueous solution
• species reactivity: human
• packaging: vial of 0.1 mL (concentrate (490M-14)), vial of 0.1 mL (concentrate (490M-14-RUO) Research Use Only), vial of 0.5 mL (concentrate (490M-15)), vial of 1.0 mL (concentrate (490M-16)), vial of 1.0 mL (concentrate (490M-16-RUO) Research Use Only), vial of 1.0 mL (pre-dilute (490M-17-RUO) Research Use Only), vial of 1.0 mL (pre-dilute ready-to-use (490M-17)), vial of 7.0 mL (pre-dilute ready-to-use (490M-18)), vial of 7.0 mL (pre-dilute ready-to-use (490M-18-RUO) Research Use Only)
• manufacturer/tradename: Cell Marque^®
• technique(s): immunohistochemistry: suitable (formalin-fixed, paraffin-embedded sections 1:25-1:100 (concentrated))
• isotype: IgG1
• control: neuroblastoma
• shipped in: wet ice
• storage temp.: 2-8°C
• visualization: cytoplasmic

Beschreibung

General description

Tyrosine Hydroxylase (TYH) is the rate-limiting enzyme of catecholamine biosynthesiss. TYH uses tetrahydrobiopterin and molecular oxygen to convert tyrosine to L-DOPA, a precursor to dopamine. Anti-TYH is sensitive and specific for peripheral neuroblastic tumors in the differential diagnosis from other tumors of childhood and shows high diagnostic utility. Anti-TYH has been shown to positively label all pheochromocytomas and sympathetic paragangliomas, and thus aids in differentiating them from their histologic mimics such as adrenocortical neoplasms.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Preparation Note

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Analysis Note

United States - IVD
Canada - RUO
European Union - IVD
Japan - RUO

Other Notes

For Technical Service please contact: 800-665-7284 or email: [email protected]

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable