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Sigma-Aldrich

6,8-Dihydroxy-1,3-pyrendisulfonsäure Dinatriumsalz

BioReagent, suitable for fluorescence, ≥97.0% (HPCE)

Synonym(e):

DHPDS

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About This Item

Empirische Formel (Hill-System):
C16H8Na2O8S2
CAS-Nummer:
61255-63-8
Molekulargewicht:
438.34
Beilstein:
8962638
MDL-Nummer:
MFCD00800283
UNSPSC-Code:
12352106
PubChem Substanz-ID:
57649723
NACRES:
NA.32

Produktlinie

BioReagent

Assay

≥97.0% (HPCE)

Form

powder

pKa 

7.33
8.53

mp (Schmelzpunkt)

≥250 °C (lit.)

Löslichkeit

DMF: soluble
H2O: soluble
methanol: soluble

Fluoreszenz

λex 405 nm; λem 456 nm in 0.1 M citrate pH 3.0
λex 458 nm; λem 498 nm in 0.1 M Tris pH 8.0

Eignung

suitable for fluorescence

SMILES String

[Na+].[Na+].Oc1cc(O)c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C16H10O8S2.2Na/c17-11-5-12(18)8-2-4-10-14(26(22,23)24)6-13(25(19,20)21)9-3-1-7(11)15(8)16(9)10;;/h1-6,17-18H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2

InChIKey

JISMNCQKTAIERN-UHFFFAOYSA-L

Anwendung

6,8-Dihydroxy-1,3-pyrenedisulfonic acid (DHPDS) is a pH-sensitive dye that may be used to measure pH changes inside cells (pHi). DHPDS is used to create charge transfer complexes for studies on nanostructure assembly.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

Gut wasserlöslicher pH-Indikator für den physiologischen Bereich

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

Gefahreneinstufungen

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Zielorgane

Respiratory system

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Gloves

Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Aron Hakonen et al.
Talanta, 80(5), 1964-1969 (2010-02-16)
This study presents a high-performance ratiometric pH optode based on the fluorophore 6,8-dihydroxypyrene-1,3-disulfonic acid (DHPDS). The two pH-sensitive terminal hydroxy groups of DHPDS facilitated dual excitation/dual emission (F(1): lambda(1,ex)=420 nm, lambda(1,em)=462 nm; F(2): lambda(2,ex)=470 nm, lambda(2,em)=498 nm) properties for ratiometric
Chao Wang et al.
Langmuir : the ACS journal of surfaces and colloids, 26(18), 14509-14511 (2010-08-21)
We have demonstrated a hierarchical self-assembly of the nanoribbons on the basis of the concept of a superamphiphile. A viologen-containing surfactant (RV) and a water-soluble electron donor, 6,8-dihydroxypyrene-1,3-disulfonic acid disodium (DHP), are mixed in water to form a charge transfer
K Hanaoka et al.
Nihon rinsho. Japanese journal of clinical medicine, 50(9), 2048-2053 (1992-09-01)
Since various cellular processes depend on changes in pH, the regulation of intracellular pH (pHi) is important both for the individual cell and for the organism. The mechanisms of the regulation of pHi can be investigated by monitoring pHi. In
F X Felberbauer et al.
Pflugers Archiv : European journal of physiology, 419(2), 215-217 (1991-09-01)
The pH-sensitive fluorescent dye 1,3-dihydroxy-pyrene-6,8-disulfonic acid (DHPDS) was used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver. Monochromatic light from a fluorometer was focused on the liver with a fiber optic, emitted light
O.S. Wolfbeis et al.
Fresenius Journal of Analytical Chemistry, 314, 119-119 (1983)

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