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160022K
MAPTrix™ Reagent
High Molecular Weight, solution, 0.5 mg/mL protein, suitable for cell culture
Synonym(e):
MAPTrix™ Technology
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 2.5 mg | Warenkorb auf Verfügbarkeit prüfen | € 175,00 € 148,75 |
Über diesen Artikel
UNSPSC Code:
12352202
NACRES:
NA.75
Biological source:
synthetic
Form:
aqueous solution
Technique(s):
cell culture | mammalian: suitable
Concentration:
0.5 mg/mL protein
Mol wt:
~36.8 kDa
€ 148,75
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Technischer Dienst
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Unterstützung erhaltenProduktname
MAPTrix™ Reagent, High Molecular Weight, aqueous solution
biological source
synthetic
sterility
Filtered sterilized solution
form
aqueous solution
mol wt
~36.8 kDa
packaging
pkg of 2.5 mg
concentration
0.5 mg/mL protein
technique(s)
cell culture | mammalian: suitable
shipped in
ambient
storage temp.
2-8°C
General description
MAPTrix™ Reagent intended for use as cell culture coating.
Application
MAPTrix™ Technology provides a true extracellular microenvironment (ECM) by presenting combinatorial peptide motifs. The ECM, defined by biochemical cues and physical cues, is a deciding factor in a wide range of cellular processes including cell adhesion, proliferation, differentiation, and expression of phenotype-specific functions.Currently existing technology offers simple and merely adequate environments that facilitate simple cell processes such as cellular adhesion.[1][2] The simple presentation of cell adhesion motifs is not optimal for controlling more integrated processes. Crosstalk among signaling pathways act synergistically to enhance cellular responses such as cell adhesion or proliferation.[3] A study showed that a combination of extracellular matrix derived peptides presented on a surface may enhance cell adhesion strength and focal adhesion assembly. The combinatorial presentation of ECM peptides on cell growth surfaces may also promote elevated proliferation rates of primary or stem cells.[4][5][6]
Features and Benefits
- Biochemically-defined, animal-free cell culture surfaces designed to enhance cell performance
- MAPTrix™ produces a uniform ECM surface that provides a highly controlled 2D extracellular microenvironment for cell cultures and related applications
- Adhesion properties of the mussel adhesive protein makes the coating reproducible & reliable
Legal Information
MAPTrix is a trademark of Kollodis Biosciences
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Dieser Artikel | |||
|---|---|---|---|
| sterility Filtered sterilized solution | sterility Filtered sterilized solution | sterility Filtered sterilized solution | sterility sterile |
| technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable | technique(s) cell culture | mammalian: suitable |
| biological source synthetic | biological source - | biological source - | biological source - |
| concentration 0.5 mg/mL protein | concentration 0.5 mg/mL protein | concentration 0.5 mg/mL protein | concentration - |
| form aqueous solution | form aqueous solution | form aqueous solution | form lyophilized powder |
| mol wt ~36.8 kDa | mol wt ~22.6 kDa | mol wt ~24.2 kDa | mol wt ~22.6 kDa |
Lagerklasse
10 - Combustible liquids
flash_point_f
Not applicable
flash_point_c
Not applicable
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Ying Meng et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 24(4), 1056-1065 (2009-11-26)
Human embryonic stem (hES) cells are pluripotent, capable of differentiating into any cell type of the body, and therefore have the ability to provide insights into mechanisms of human development and disease, as well as to provide a potentially unlimited
Stephanie J Ellis et al.
Cell and tissue research, 339(1), 121-130 (2009-07-10)
The regulation of stem cell behavior and maintenance typically involves the integration of both intrinsic and extrinsic cues. One such external cue, integrin-mediated cell adhesion to the extracellular matrix, plays an important part in regulating stem cell function and maintenance.
Samuel Schmidt et al.
Cell and tissue research, 339(1), 83-92 (2009-11-19)
Adhesion and migration are integrated cell functions that build, maintain and remodel the multicellular organism. In migrating cells, integrins are the main transmembrane receptors that provide dynamic interactions between extracellular ligands and actin cytoskeleton and signalling machineries. In parallel to
Global Trade Item Number
| SKU | GTIN |
|---|---|
| 160022K-2.5MG | 04061838744920 |