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147M-9

CD45RO (UCHL-1) Mouse Monoclonal Antibody

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Über diesen Artikel

NACRES:
NA.41
UNSPSC Code:
12352203
Conjugate:
unconjugated
Clone:
UCHL-1, monoclonal
Application:
IHC (p)
Citations:
7
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Technischer Dienst
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biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

culture supernatant

antibody product type

primary antibodies

clone

UCHL-1, monoclonal

description

For In Vitro Diagnostic Use in Select Regions (See Chart)

form

buffered aqueous solution

species reactivity

human

packaging

vial of 0.1 mL concentrate (147M-94), vial of 0.5 mL concentrate (147M-95), bottle of 1.0 mL predilute (147M-97), vial of 1.0 mL concentrate (147M-96), bottle of 7.0 mL predilute (147M-98)

manufacturer/tradename

Cell Marque®

technique(s)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

isotype

IgG2aκ

control

tonsil

shipped in

wet ice

storage temp.

2-8°C

visualization

membranous

Gene Information

human ... PTPRC(5788)

General description

Anti-CD45RO (T-Cell, Pan) antibody reacts with thymocytes and activated T-cells, but only on a subpopulation of resting T-cells. This antibody shows no reactivity with B-cells making it a good marker for T-cell tumors. In addition, granulocytes and monocytes are also labeled with this antibody. T-Cell, Pan has been designated as CD45RO at The International Leukocyte Typing Workshop.

Physical form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Preparation Note

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Analysis Note


IVD

IVD

IVD

RUO

Other Notes

CD45RO Positive Control Slides, Product No. 147S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).
For Technical Service please contact: 800-665-7284 or email: [email protected]

Legal Information

Cell Marque is a registered trademark of Merck KGaA, Darmstadt, Germany


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B Falini et al.
Human pathology, 21(6), 624-629 (1990-06-01)
Monoclonal antibodies (mAbs) directed against the leucocyte common (CD45) antigen have been proposed as a useful tool for the differential diagnosis between malignant lymphomas (CD45+) and poorly differentiated nonhemopoietic tumors (CD45-). Thanks to the availability of mAbs directed against fixative-resistant
J A Tworek et al.
American journal of clinical pathology, 110(5), 582-589 (1998-11-05)
Small lymphocytic lymphoma (SLL), mantle cell lymphoma (MCL), and SLL plasmacytoid (SLLP) are malignant neoplasms of small B cells that may have overlapping cytologic features. Entities such as SLL with irregular nuclear contours may pose additional diagnostic difficulties. We investigated
P A Hall et al.
Journal of clinical pathology, 40(2), 151-156 (1987-02-01)
The use of the murine monoclonal antibody MB2 for identifying B lymphocytes in routinely processed tissue was evaluated and contrasted with the use of the monoclonal antibody UCHL1 for identifying T cells. One hundred and sixty eight surgical biopsy specimens



Global Trade Item Number

SKUGTIN
147M-950841683125051
147M-940841683125044
147M-980841683125082
147M-970841683125075
147M-960841683125068

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