07668
Echinacosid
98% (HPLC)
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Über diesen Artikel
Empirische Formel (Hill-System):
C35H46O20
CAS-Nummer:
Molekulargewicht:
786.73
NACRES:
NA.32
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
Beilstein/REAXYS Number:
4778612
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Unterstützung erhaltenInChI
1S/C35H46O20/c1-14-24(42)26(44)29(47)35(51-14)55-32-30(48)34(49-9-8-16-3-6-18(38)20(40)11-16)53-22(13-50-33-28(46)27(45)25(43)21(12-36)52-33)31(32)54-23(41)7-4-15-2-5-17(37)19(39)10-15/h2-7,10-11,14,21-22,24-40,42-48H,8-9,12-13H2,1H3/b7-4+/t14-,21+,22+,24-,25+,26+,27-,28+,29+,30+,31+,32+,33+,34+,35-/m0/s1
InChI key
FSBUXLDOLNLABB-ISAKITKMSA-N
assay
98% (HPLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
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General description
Echinacoside (ECH) is a natural secondary metabolite, a phenylethanoid glycoside (PhG) found in the roots and stems of many plants. It is a water-soluble compound. Echinacoside was first isolated from the roots of Echinacea angustifolia (coneflower). It can also be sourced from other medicinal plants such as Echinacea purpurea (purple coneflower) and Cistanche salsa.
Biochem/physiol Actions
Caffeic acid glycoside found in herbal medicine. Potential therapeutic for Parkinson′s disease.
Echinacoside elicits neuroprotective properties against neurological disorders and on tumor necrosis factor-alpha (TNFα)-induced apoptosis in human neuroblastoma (SH-SY5Y) cells. It also displays antioxidant and free radical scavenging properties. ECH exerts hepatoprotective and anti-cancer properties.
Echinacoside is a secondary metabolite found in plants, specifically in the roots of Echinacea angustifolia (cone flower) , E. purpurea (purple coneflower) and Cistanche salsa. It has been shown to possess anti-oxidant and free radical scavenging properties, to have neuroprotective effects and to prevent liver injuries. It has also been found to be antibiotic and anti-inflammatory.[1] Echinacoside was shown to promote proliferation of intestinal epithelial cells by increasing TGF-β1 expression.[2]
Packaging
Bottomless glass bottle. Contents are inside inserted fused cone.
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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Hinyokika kiyo. Acta urologica Japonica, 38(2), 167-172 (1992-02-01)
Hammock nonrefluxing ureteroileal anastomosis was performed on 14 patients who had urinary tract reconstruction using ileal conduit (4), Kock pouch (3), modified Kock pouch with plicated efferent limb (1) and ileal neobladder (6). Radiographic examinations showed ureteral reflux of contrast
Monika E Czerwińska et al.
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The genus Ligustrum (Oleaceae) is distributed in Europe and Asia (south China and Korea), where it is used to prevent hypertension, sore throats, inflammation and diabetes. The main groups of compounds in extracts of Ligustrum vulgare are biologically active secoiridoids
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Murine bone marrow cells were examined in an in vitro assay to determine whether stress modulates the migration of prethymic stem cells to thymus supernatant. Adult CBA/J mice were either restraint or sound stressed for two hours daily for five
Min Zhu et al.
Journal of neurochemistry, 124(4), 571-580 (2012-11-30)
Neurotrophins exert their physiological functions mainly through Trk receptors, and the neurotrophic signaling network is critical to the survival of neurons. However, therapeutic use of neurotrophins in treating neurodegenerative diseases is hampered by a number of pharmacological challenges, and the
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