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S9876

Sulfathiazol

Sulfathiazole

Synonym(e):

2-Sulfanilamidothiazol, 4-Amino-N-(2-thiazolyl)-benzolsulfonamid, N1-(2-Thiazolyl)-sulfanilamid

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PackungsgrößeSKUVerfügbarkeitPreis
100 g
Warenkorb auf Verfügbarkeit prüfen
€ 70,30

Über diesen Artikel

Empirische Formel (Hill-System):
C9H9N3O2S2
CAS-Nummer:
Molekulargewicht:
255.32
UNSPSC Code:
41116107
NACRES:
NA.24
PubChem Substance ID:
EC Number:
200-771-5
Beilstein/REAXYS Number:
226178
MDL number:

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grade

analytical standard

Quality Level

agency

EPA 1694

form

powder

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

200-202 °C (lit.)

application(s)

clinical testing

SMILES string

Nc1ccc(cc1)S(=O)(=O)Nc2nccs2

InChI

1S/C9H9N3O2S2/c10-7-1-3-8(4-2-7)16(13,14)12-9-11-5-6-15-9/h1-6H,10H2,(H,11,12)

InChI key

JNMRHUJNCSQMMB-UHFFFAOYSA-N

General description

Sulfathiazole is a broad-spectrum antibacterial drug, belonging to the class of sulfonamides, used in veterinary and human medication for the treatment of infections. It is also involved in promoting growth of livestock and fish.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Sulfathiazole is used as an analytical reference standard for the quantification of the analyte in meat, and honey samples using different chromatography techniques.

Biochem/physiol Actions

Sulfonamid Antibiotikum, blockiert die Synthese von Dihydrofolsäure durch Inhibierung des Enzyms Dihydropteroatsynthase.
Wirkungsweise: Inhibiert Folsäuresynthese in Prokaryoten.
Antimikrobielles Spektrum: Gram positive, Gram negative, Chlamydia
Mode of Resistance: Abänderung der Dihydropteroatsynthase oder alternativer Weg für Folsäuresynthese.

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Dieser Artikel
469021636504S2158000
Sulfathiazole European Pharmacopoeia (EP) Reference Standard

S2158000

Sulfathiazole

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

application(s)

clinical testing

application(s)

clinical testing

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

form

powder

form

-

form

-

form

-

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

-

grade

analytical standard

grade

analytical standard

grade

pharmaceutical primary standard

grade

pharmaceutical primary standard

mp

200-202 °C (lit.)

mp

200-202 °C (lit.)

mp

200-202 °C (lit.)

mp

200-202 °C (lit.)


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pictograms

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signalword

Warning

Hazard Classifications

Aquatic Chronic 3 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

11 - Combustible Solids

wgk

WGK 2

ppe

dust mask type N95 (US), Eyeshields, Gloves



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Comparison of separation conditions and ionization methods for the liquid chromatography?mass spectrometric determination of sulfonamides
Kim H-D and Lee WD
Journal of Chromatography A, 984(1), 153-158 (2003)
Determination of sulfonamides in meat by liquid chromatography coupled with atmospheric pressure chemical ionization mass spectrometry
Kim H-D, et al.
Bull. Korean Chem. Soc., 23(11), 1590-1594 (2002)
Quantitative LC/MS-MS determination of sulfonamides and some other antibiotics in honey
Kaufmann A, et al.
Journal of AOAC (Association of Official Analytical Chemists) International, 85(4), 853-860 (2002)



Global Trade Item Number

SKUGTIN
S9876-250G04061836964573
S9876-100G04061836964566

Questions

Reviews

Active Filters

    • Review 1
    • Votes 2
    2 out of 5 stars.

    Required extra work

    Needed to be recrystallized - MS showed contamination with Na.

    Helpful?

    1. Response from Merck KGaA:

      Thank you for your review. This product is designated for research and laboratory use and undergoes basic qualtiy control testing. The minimum purity of any given lot will be 98% by HPLC. We do not further identify the impurities nor do we set minimum specifications on any potential contaminant. It is possible there there are trace amounts of residual salts and/or solvents which may interfere with more sensitive applications. We encourage customers who experience problems with our products to call or email us for additional technical support. Please visit https://www.sigmaaldrich.com/US/en/support/customer-support to submit a Product Technical Inquiry.