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S2002

Natriumazid

ReagentPlus®, ≥99.5%

Sodium azide

Synonym(e):

Stickstoffwasserstoffsäure Natriumsalz

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PackungsgrößeSKUVerfügbarkeitPreis
5 g

Ab HEUTE lieferbarvonSchnelldorf

€ 20,60
25 g

Ab HEUTE lieferbarvonSchnelldorf

€ 42,00
100 g

Ab HEUTE lieferbarvonSchnelldorf

€ 81,90
500 g

Ab HEUTE lieferbarvonSchnelldorf

€ 173,00
2 kg

Ab HEUTE lieferbarvonSchnelldorf

€ 647,00

Über diesen Artikel

Lineare Formel:
NaN3
CAS-Nummer:
Molekulargewicht:
65.01
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352201
EC Number:
247-852-1
MDL number:

€ 20,60


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biological source

synthetic (inorganic)

Quality Segment

product line

ReagentPlus®

assay

≥99.5%

form

powder

storage condition

(Tightly closed. Dry. Keep in a well-ventilated place. Do not store near acids.)

technique(s)

cell based assay: suitable, immunohistochemistry: suitable

color

white

mp

370-425 °C

solubility

soluble 65 g/L at 20 °C (completely)

suitability

suitable for chromatography, suitable for derivatization

application(s)

sample preparation

SMILES string

[Na]N=[N+]=[N-]

InChI

1S/N3.Na/c1-3-2;/q-1;+1

InChI key

PXIPVTKHYLBLMZ-UHFFFAOYSA-N

General description

Natriumazid (NaN3) ist ein starker Inhibitor – ein wasserlösliches, kristallines, geruchloses Pulver. Es ist weithin für seine vielseitige Anwendbarkeit bekannt und spielt eine zentrale Rolle in der Molekularbiologie, der Zellkultivierung und der biochemischen Forschung. Darüber hinaus ist es ein metabolischer Inhibitor, der die oxidative Phosphorylierung hemmt. In der Zellkultur bewahrt es die Integrität Ihrer Zelllinien.

Application

Natriumazid eignet sich für die Verwendung in der Histopathologie zur Vorbereitung und Aufbewahrung von Gewebeproben.[1] [2] Es wird auch als Bestandteil von Färbepuffern (HEPES-Puffer) für die Ganzkörper(„Whole-Mount“)-Immunmarkierung verwendet.
Katalysator für:

  • Oxidative Decarboxylierung
  • Michael-Additionsreaktionen[3]

Reagenz zur Synthese von
  • blau fluoreszierenden Copolymeren
  • Metallphosphonate[4]
  • Arene mittels Aminierung
Mittels Baylis-Hillman-Reaktionen gewonnene Acetate wie Ethyl 2-(acetoxyphenylmethyl)acrylat können in wässrigem Medium eine nukleophile Verdrängungsreaktion durch Natriumazid durchlaufen, um Ethyl-(E)-2-azidomethyl-3-phenylpropenoat zu bilden.

Biochem/physiol Actions

Natriumazid wird klinisch als Konservierungsmittel in Verdünnungsflüssigkeit für die Zählung roter Blutkörperchen verwendet.[5] Es verhindert das Capping und die Internalisierung von fluoreszierenden oberflächengebundenen Antikörpern in verschiedenen wissenschaftlichen Anwendungen, einschließlich Durchflusszytometrie.

Other Notes

Füllen Sie bitte dieses Formular aus, um weitere Informationen zu unserem Sortiment an Biochemikalien zu erhalten.

Legal Information

ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany

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Dieser Artikel
1.066887129071289
biological source

synthetic (inorganic)

biological source

-

biological source

-

biological source

-

assay

≥99.5%

assay

-

assay

≥99.0% (T)

assay

≥99.5% (T)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

-

form

crystals

form

crystals

solubility

soluble 65 g/L at 20 °C (completely)

solubility

420 g/L

solubility

H2O: 0.1 g/mL, clear, colorless

solubility

H2O: 1 M at 20 °C, clear, colorless

storage condition

(Tightly closed. Dry. Keep in a well-ventilated place. Do not store near acids.)

storage condition

-

storage condition

-

storage condition

-


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Danger

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2 Oral

target_organs

Brain

supp_hazards

Lagerklasse

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c

Not applicable



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Protokolle

Detailed ELISA protocols cover indirect and capture ELISA techniques, recommending products for sandwich and indirect ELISA experiments.

Antibody purification protocols yield preparations containing endogenous IgG alongside specific antibodies.

Verwandter Inhalt


Calcium uptake by rat kidney mitochondria.
DeLuca HF and Engstrom GW.
Proceedings of the National Academy of Sciences of the USA, 47(11), 1744-1750 (1961)
A critical review of published methods for analysis of red cell antigen-antibody reactions by flow cytometry, and approaches for resolving problems with red cell agglutination
Patricia A Arndt , George Garratty
Transfusion Medicine Reviews, 24(3), 174-192 (2010)
Nucleophilic displacement by azide and cyanide on Baylis-Hillman acetates in water.
Yadav JS, et al.
Tetrahedron Letters, 46(16), 2761-2763 (2005)



Global Trade Item Number

SKUGTIN
S2002-2KG04061836916053
S2002-25G04061835549290
S2002-25KG04061833512913
S2002-500G04061835549306
S2002-100G04061835549283
S2002-5G04061835549313

Questions

1–8 of 8 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  3. what do you mean by Bioxtra and reagentplus? How much difference are there between two grades.

    1 answer
    1. Products that fall under the BioXtra portfolio undergo stringent testing protocols that may include trace metal analysis and specialized suitability testing, such as hybridoma or mouse embryo culture. These products include application-specific formulations such as tablets and prepared solutions.

      Products that fall under the ReagentPlus portfolio are designed for general laboratory use and have purities that are greater or equal to 95%.

      Helpful?

  4. How does Product S2002, Sodium azide, inhibit certain metalloenzymes?

    1 answer
    1. The mechanism of sodium azide inhibition may be due to metal ion complexation and displacement from the enzyme.

      Helpful?

  5. Are there any hazards associated with the disposal of Product S2002, Sodium azide?

    1 answer
    1. Sodium azide can form metal azides.  If you have metal pipes for your plumbing, you should not dispose of solutions down them.

      Helpful?

  6. How stable are solutions of Product S2002, Sodium azide?

    1 answer
    1. At a neutral pH sodium azide solutions are fairly stable.  Under acidic conditions it is converted to hydrazoic acid, a volatile gas.

      Helpful?

  7. How can I determine the concentration of sodium azide in solution?

    1 answer
    1. Sodium azide forms a 3,5-dinitrobenzoyl derivative that can be quantified by liquid chromatography.  This method is reported in the Journal of Chromatography, 5, 597 (1982).

      Helpful?

  8. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

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