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P5631

Sigma-Aldrich

Metallphthalein

powder

Synonym(e):

o-Cresolphthalein-Komplexon, o-Kresolphthalein-3′,3″-bis-methyliminodiessigsäure, o-Kresolphthalexon, Phthaleinpurpur

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About This Item

Empirische Formel (Hill-System):
C32H32N2O12
CAS-Nummer:
2411-89-4
Molekulargewicht:
636.60
Beilstein:
381994
EG-Nummer:
219-318-8
MDL-Nummer:
MFCD00005911
UNSPSC-Code:
12171500
PubChem Substanz-ID:
24898682
NACRES:
NA.47

Form

powder

Qualitätsniveau

200

Farbe

white to off-white

mp (Schmelzpunkt)

181-185 °C (dec.) (lit.)

Löslichkeit

methanol: 1 mg/mL

Eignung

suitable for determination of calcium

Anwendung(en)

diagnostic assay manufacturing
hematology
histology

Lagertemp.

room temp

SMILES String

Cc1cc(cc(CN(CC(O)=O)CC(O)=O)c1O)C2(OC(=O)c3ccccc23)c4cc(C)c(O)c(CN(CC(O)=O)CC(O)=O)c4

InChI

1S/C32H32N2O12/c1-17-7-21(9-19(29(17)43)11-33(13-25(35)36)14-26(37)38)32(24-6-4-3-5-23(24)31(45)46-32)22-8-18(2)30(44)20(10-22)12-34(15-27(39)40)16-28(41)42/h3-10,43-44H,11-16H2,1-2H3,(H,35,36)(H,37,38)(H,39,40)(H,41,42)

InChIKey

IYZPEGVSBUNMBE-UHFFFAOYSA-N

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Allgemeine Beschreibung

o-Cresolphthalein Complexone is a pH indicator dye commonly used for the calorimetric determination of calcium in serum.

Anwendung

o-Cresolphthalein Complexone has been used in the estimation of calcium in serum samples based on the reaction of Ca2+ with o-cresolphthalein complexone in an alkaline solution.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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Analysenzertifikate (COA)

Lot/Batch Number
WXBF4083V
WXBF1358V
SHBQ7561
0000256524
0000291210

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Sigma-Aldrich

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Sigma-Aldrich

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C M Corns et al.
Annals of clinical biochemistry, 24 ( Pt 4), 345-351 (1987-07-01)
The reasons for the non-linearity of the standard curve for the calcium-cresolphthalein complexone reaction have been investigated. Calcium forms both 1:1 and 2:1 complexes with cresolphthalein complexone; at low calcium concentrations the 1:1 complex predominates and causes non-linearity. At high
James H Wible et al.
Radiology, 233(1), 158-164 (2004-09-30)
To measure serum calcium concentration with three different analytic methods after administration of gadoversetamide and three other gadolinium chelates in dogs. Six dogs were injected with 0.1-, 0.3-, 1.0-, and 3.0-mmol/kg doses of gadoversetamide; 1.0-mmol/kg doses of gadodiamide, gadopentetate, and
Sandra F Williams et al.
Mayo Clinic proceedings, 80(12), 1655-1657 (2005-12-14)
Severe hypocalcemia may require prompt intervention to avoid life-threatening consequences. We report a case in which a 78-year-old man had a critically low serum calcium level measured with use of standard colorimetric assay after gadodiamide administration during magnetic resonance angiography.
M A Koupparis et al.
Clinical chemistry, 28(10), 2149-2152 (1982-10-01)
We describe the measurement of total calcium and magnesium in serum with an automated microcomputer-controlled stopped-flow analyzer. The calcium method is based on the cresolphthalein complexone procedure, with 2-amino-3-methyl-1-propanol as the alkalinizing agent. The assay, performed on 60-fold prediluted samples
R J Liedtke et al.
Clinical chemistry, 27(12), 2025-2028 (1981-12-01)
We describe an automated method for calcium assay, for use with the Cobas-Bio centrifugal analyzer. Calcium is reacted with cresolphthalein complexone and the absorbance of the calcium--dye complex at 575 nm is measured. EDTA is then added to break up
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