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N6142

Supelco

Nabumeton

analytical standard

Synonym(e):

4-(6-Methoxy-2-naphthyl)-2-butanon

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About This Item

Empirische Formel (Hill-System):
C15H16O2
CAS-Nummer:
42924-53-8
Molekulargewicht:
228.29
MDL-Nummer:
MFCD00079518
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329818660
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

100

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

forensics and toxicology
pharmaceutical (small molecule)
veterinary

Format

neat

SMILES String

COc1ccc2cc(CCC(C)=O)ccc2c1

InChI

1S/C15H16O2/c1-11(16)3-4-12-5-6-14-10-15(17-2)8-7-13(14)9-12/h5-10H,3-4H2,1-2H3

InChIKey

BLXXJMDCKKHMKV-UHFFFAOYSA-N

Angaben zum Gen

human ... PTGS1(5742) , PTGS2(5743)

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Verwandte Kategorien

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Nicht-selektives, nicht-steroides entzündungshemmendes Arzneimittel (NSAID)

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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Analysenzertifikate (COA)

Lot/Batch Number
MKCN3727
MKCG6105
MKCD9732
MKBZ6732V
MKBT7117V

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If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

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Solubility of triamcinolone acetonide and other anti-inflammatory drugs in silicone oil: implications for Therapeutic Efficacy.
José Carlos Pastor et al.
Retina (Philadelphia, Pa.), 28(9), 1247-1250 (2008-07-17)
Michael Crothers et al.
International journal of pharmaceutics, 358(1-2), 303-306 (2008-04-18)
The solubilisation of two poorly soluble drugs, furosemide and nabumetone, in micellar solutions of diblock copolymers of ethylene oxide and styrene oxide has been studied at 25 and 37 degrees C and solubilisation capacities compared with published values for griseofulvin
S Paul et al.
JNMA; journal of the Nepal Medical Association, 48(174), 121-125 (2010-04-15)
Aceclofenac, a NSAID is widely used in the treatment of pain and inflammation associated with osteoarthritis. Nabumetone, a recently developed preferential cyclo-oxygenase 2 inhibitor has also proved to be equally effective. The present study was undertaken to evaluate the 'real
Kaori Matsumoto et al.
Biological & pharmaceutical bulletin, 34(5), 734-739 (2011-05-03)
The cytochrome P450 (CYP) isoforms that catalyze the oxidation metabolism of 6-methoxy-2-napthylacetic acid (6-MNA), an active metabolite of nabumetone, were studied in rats and humans. Using an extractive reversed-phase HPLC assay with fluorescence detection, monophasic Michaelis-Menten kinetics was obtained for
Jinhyun Kim et al.
Clinical therapeutics, 31(12), 2860-2872 (2010-01-30)
S-adenosylmethionine (SAMe) has antiinflammatory and analgesic effects and has been reported to ameliorate the pain and dysfunction of osteoarthritis (OA). The metabolism of SAMe can be affected by geographic or ethnic factors. However, its efficacy and tolerability versus NSAIDs have
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