A9797

Ambroxol -hydrochlorid

analytical standard

• Synonym(e): 2-Amino-3,5-dibrom-N-(trans-4-hydroxycyclohexyl)-benzylamin
• Empirische Formel (Hill-System): C₁₃H₁₈Br₂N₂O · HCl
• CAS-Nummer: 23828-92-4
• Molekulargewicht: 414.56
• NACRES: NA.24
• PubChem Substance ID: 329771060
• UNSPSC Code: 41116107
• EC Number: 245-899-2
• MDL number: MFCD00078932

Eigenschaften

• grade: analytical standard
• Quality Segment: 100
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): forensics and toxicology; pharmaceutical (small molecule); veterinary
• format: neat
• storage temp.: 2-8°C
• SMILES string: Cl.Nc1c(Br)cc(Br)cc1CN[C@@H]2CC[C@@H](O)CC2
• InChI: 1S/C13H18Br2N2O.ClH/c14-9-5-8(13(16)12(15)6-9)7-17-10-1-3-11(18)4-2-10;/h5-6,10-11,17-18H,1-4,7,16H2;1H/t10-,11-;
• InChI key: QNVKOSLOVOTXKF-PFWPSKEQSA-N

Beschreibung

General description

Ambroxol hydrochloride is a mucolytic expectorant and a metabolite of bromhexine. It is used in the treatment of respiratory disorders characterized by viscous or excessive mucus.

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Ambroxol hydrochloride standard may be used as a reference standard in the determination of ambroxol hydrochloride in pharmaceutical preparations using reversed-phase sequential injection chromatography (RP-SIC) and reversed-phase high performance liquid chromatography (RP-HPLC).

Biochem/physiol Actions

Bromhexin Metabolit.
A Nav1.8-preferring sodium channel blocker

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves