Fortfahren mit
A115
Amitriptylin-Metabolit, (±)-E-10-hydroxyliert-
analytical standard
Synonym(e):
(±)-(E)-5-[3-(Dimethylamino)-propyliden]-10,11-dihydro-5H-dibenzo[a,d]cyclohepten-10-ol
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|---|---|---|
| 2 mg | Warenkorb auf Verfügbarkeit prüfen | € 281,00 € 210,75 |
Über diesen Artikel
Empirische Formel (Hill-System):
C20H23NO
CAS-Nummer:
Molekulargewicht:
293.40
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
€ 210,75
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Unterstützung erhaltenQuality Level
grade
analytical standard
form
solid
technique(s)
HPLC: suitable, gas chromatography (GC): suitable
color
white
mp
97-99 °C
solubility
0.1 M HCl: soluble, H2O: insoluble, methanol: soluble
application(s)
forensics and toxicology
pharmaceutical (small molecule)
format
neat
SMILES string
CN(C)CC\C=C1/c2ccccc2CC(O)c3ccccc13
Verwandte Kategorien
Application
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions
Metabolit von Amitriptylin, tricyclisches Antidepressivum; Chromatographie-Standard.
Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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U Breyer-Pfaff et al.
Clinical pharmacology and therapeutics, 52(4), 350-358 (1992-10-01)
In 26 hospitalized patients with depression, a combined pharmacogenetic test with dextromethorphan, a substrate of cytochrome P450IID6, and mephenytoin, the S-form of which is hydroxylated by a P450IIC isozyme, was carried out before amitriptyline therapy. Metabolites were determined in 24-hour
D S Robinson et al.
Journal of clinical psychopharmacology, 5(2), 83-88 (1985-04-01)
As part of a double-blind clinical trial comparing phenelzine and amitriptyline in outpatients with predominantly major depressive disorder, plasma tricyclic antidepressant drug concentrations were measured in 83 amitriptyline-treated patients. In 29 of these patients, hydroxymetabolites were also assayed. Patients were
X Zhang
Zhonghua shen jing jing shen ke za zhi = Chinese journal of neurology and psychiatry, 25(4), 196-198 (1992-08-01)
The serum concentrations of amitriptyline and its 3 metabolites--nortriptyline, 10-hydroxy-amitriptyline and 10-hydroxy-nortriptyline were determined in 18 depressive patients treated with amitriptyline for 6 weeks. The relationships between the serum concentrations and the clinical effects were statistically analyzed and showed significant
F Coudoré et al.
Fundamental & clinical pharmacology, 8(6), 525-531 (1994-01-01)
Kinetics of amitriptyline (AMI), its demethylated metabolites nortriptyline (NOR) and demethylnortriptyline (DM-NOR), and its hydroxylated metabolites, the E and Z isomers or 10-hydroxy-amitriptyline (E- and Z-10-OH-AMI) and of 10-hydroxynortriptyline (E- and Z-10-OH-NOR) were studied in plasma and brain from Swiss
K Shimoda et al.
Journal of clinical psychopharmacology, 15(3), 175-181 (1995-06-01)
We measured the concentrations in plasma of amitriptyline and its metabolites, nortriptyline and geometric isomers of 10-hydroxynortriptyline and 10-hydroxyamitriptyline, in 73 Japanese psychiatric patients receiving amitriptyline hydrochloride (Tryptanol; Banyu Pharmaceutical Co. Ltd., Tokyo, Japan) by high-performance liquid chromatography. Although there
Global Trade Item Number
| SKU | GTIN |
|---|---|
| A115-2MG | 04061833646144 |
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