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Chinin

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym(e):

6′-Methoxycinchonidin

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About This Item

Empirische Formel (Hill-System):
C20H24N2O2
CAS-Nummer:
130-95-0
Molekulargewicht:
324.42
Beilstein:
91867
EG-Nummer:
205-003-2
MDL-Nummer:
MFCD00198096
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329761562
NACRES:
NA.24

Qualität

certified reference material
TraceCERT®

Qualitätsniveau

300

Produktlinie

TraceCERT®

Haltbarkeit

limited shelf life, expiry date on the label

Hersteller/Markenname

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Lagerbedingungen

under inert gas

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

173-175 °C (lit.)

Anwendung(en)

food and beverages

Format

neat

SMILES String

COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1

InChIKey

LOUPRKONTZGTKE-WZBLMQSHSA-N

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Allgemeine Beschreibung

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

blockiert Kaliumkanäle

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Vorsicht

Store under argon.

Rechtliche Hinweise

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302,H317

Gefahreneinstufungen

Acute Tox. 4 Oral - Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1

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Analysenzertifikate (COA)

Lot/Batch Number
BCCF7920
BCBV4559
BCBM5794V
BCBG6955V
BCBG6955

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George Praygod et al.
Malaria journal, 7, 210-210 (2008-10-22)
The efficacy of intravenous quinine, which is the mainstay for treating severe malaria in children, is decreasing in South East Asia and Africa. Artemisinin derivatives are a potential alternative to quinine. However, their efficacy compared to quinine in treating severe
Hmwe Hmwe Kyu et al.
Bulletin of the World Health Organization, 87(12), 896-904 (2010-05-11)
To summarize the existing evidence on the efficacy of artemether and arteether, two artemisinin derivatives, versus quinine for treating cerebral malaria in children. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and the http://clinicaltrials.gov web site. We
Jane Achan et al.
Malaria journal, 10, 144-144 (2011-05-26)
Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex dosing regimens, and the availability of more efficacious anti-malarial drugs. This
Karen M Kiang et al.
Archives of disease in childhood. Education and practice edition, 98(1), 7-15 (2012-11-23)
Since the 2010 publication in this journal of a review of the management of imported malaria for U.K. children, new evidence for the treatment of both severe and uncomplicated malaria has been published. This review discusses these new data and
B Darpo et al.
Clinical pharmacology and therapeutics, 97(4), 326-335 (2015-02-12)
The QT effects of five "QT-positive" and one negative drug were tested to evaluate whether exposure-response analysis can detect QT effects in a small study with healthy subjects. Each drug was given to nine subjects (six for placebo) in two
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