04646

Hamamelitannin

≥98.0% (HPLC)

• Synonym(e): 2-C-(Hydroxymethyl)-D-ribofuranose-2′,5-digallat, Hamamelofuranose-2′,5-digallat
• Empirische Formel (Hill-System): C₂₀H₂₀O₁₄
• CAS-Nummer: 469-32-9
• Molekulargewicht: 484.36
• NACRES: NA.25
• PubChem Substance ID: 329747966
• UNSPSC Code: 41116107
• EC Number: 207-416-3
• MDL number: MFCD00017418

Eigenschaften

• Quality Segment: 100
• assay: ≥98.0% (HPLC)
• form: powder or crystals
• application(s): food and beverages; metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: OC1O[C@H](COC(=O)c2cc(O)c(O)c(O)c2)[C@@H](O)[C@]1(O)COC(=O)c3cc(O)c(O)c(O)c3
• InChI: 1S/C20H20O14/c21-9-1-7(2-10(22)14(9)25)17(28)32-5-13-16(27)20(31,19(30)34-13)6-33-18(29)8-3-11(23)15(26)12(24)4-8/h1-4,13,16,19,21-27,30-31H,5-6H2/t13-,16-,19?,20-/m1/s1
• InChI key: FEPAFOYQTIEEIS-IZUGRSKYSA-N

Beschreibung

General description

Hamamelitanninis a tannin derived from the bark and leaves of Hamamelis virginiana(witch hazel).

Application

Hamamelitannin can be used to study chromatography, aromatics, esters, hamamelis, heterocyclics, natural compounds, phenols, phytopharma standards, polyhydroxy compounds, and tannins. It also significantly reduces biofilm metabolic activity of the following bacteria: Staphylococcus epidermidis, Staphylococcus aureus, Acinetobacter baumannii, and Candida albicans strains. Hamamelitannin displays specific cytotoxic activity against colon cancer cells. It has been used in a study to determine that quorum-sensing inhibitors increase the success of antibiotic treatment by increasing the susceptibility of bacterial biofilms and/or by increasing host survival following infection.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)