The Journal of biological chemistry, 281(15), 9925-9934 (2006-02-10)
The arsRDABC operon of Escherichia coli plasmid R773 encodes the ArsAB extrusion pump for the trivalent metalloids As(III) and Sb(III). ArsA, the catalytic subunit has two homologous halves, A1 and A2. Each half has a consensus signal transduction domain that
Molecular and biochemical parasitology, 158(1), 95-99 (2008-01-01)
Pentavalent antimonial containing drugs (SbV) are the mainstay for the control of the protozoan parasite Leishmania but resistance to this class of drug is now prevalent in several endemic areas. We describe here the use of functional cloning where an
Case records of the Massachusetts General Hospital. Case 22-2012. A 34-year-old man with intractable vomiting after ingestion of an unknown substance.
Wendy Macías Konstantopoulos et al.
The New England journal of medicine, 367(3), 259-268 (2012-07-20)
Trivalent antimonial drugs, including tartar emetic (TA), are known to induce important cardiotoxicity observed by electrocardiographic abnormalities. Liposome encapsulation was found to reduce the overall acute toxicity of TA. The present work investigated the cardiovascular parameters alterations of rats submitted
Antimicrobial agents and chemotherapy, 49(10), 4406-4409 (2005-09-29)
We previously documented the induction of Leishmania amastigote apoptosis by trivalent antimony (SbIII) and nitric oxide (NO). We demonstrate here that SbIII-resistant amastigotes were resistant to NO toxicity when delivered extracellularly by NO donors or intracellularly via macrophage activation. Shared
Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..
