SCC225

YUMM 1.3 Mouse Melanoma Cell Line

Mouse

• Synonym(e): Yale University Mouse Melanoma 1.3 cell line, Yale University Mouse Melanoma cell line
• UNSPSC-Code: 41106514
• NACRES: NA.81

Eigenschaften

• product name: YUMM 1.3 Mouse Melanoma Cell Line,
• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Verpackung: vial of ≥1X10⁶ vial
• Hersteller/Markenname: Millipore
• Methode(n): cell culture | mammalian: suitable
• Versandbedingung: liquid nitrogen
• Lagertemp.: −196°C

Beschreibung

Allgemeine Beschreibung

YUMM1.3 cells are syngeneic with the immunocompetent C57BL/6 mouse background and retain genetic markers of the Braf/Pten mouse models, characterized by activation of Braf and inactivation of Pten and Cdkn2a.

Anwendung

• Each vial contains >1X10⁶ viable cells.
• YUMM1.3 cells are tested negative for infectious diseases by a Mouse Essential CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are verified to be of mouse origin and negative for inter-species contamination from rat, chinese hamster, Golden Syrian hamster, human and non-human primate (NHP) as assessed by a Contamination CLEAR panel by Charles River Animal Diagnostic Services.
• Cells are negative for mycoplasma contamination.

Leistungsmerkmale und Vorteile

​ The YUMM cell models recapitulate genetic drivers found in a significant proportion of human melanomas. YUMM1.3 cells retain genetic markers of the Braf/Pten mouse models, characterized by activation of Braf and inactivation of Pten and Cdkn2a, in which

Zielbeschreibung

Immunocompetent genetically-engineered mouse models harboring discrete genetic drivers of melanoma are essential for studying potential immunotherapies but are limited by the need to maintain colonies of multiple genotypes necessary to generate mouse mode

Lagerung und Haltbarkeit

YUMM1.3 cells should be stored in liquid nitrogen until use. The cells can be cultured for at least 10 passages after initial thawing without significantly affecting the cell marker expression and functionality.

Sonstige Hinweise

This product is intended for sale and sold solely to academic institutions for internal academic research use per the terms of the “Academic Use Agreement” as detailed in the product documentation. For information regarding any other use, please contact l

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable