MABC532
Anti-PTHrP Antibody, clone 4C4.1
clone 4C4.1, from mouse
Synonym(e):
Parathyroid hormone-related protein, PTHrP, PTH-rP, Parathyroid hormone-like protein, PLP
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| Packungsgröße | SKU | Verfügbarkeit | Preis |
|---|
Über diesen Artikel
biological source
mouse
Quality Level
conjugate
unconjugated
antibody form
purified immunoglobulin
antibody product type
primary antibodies
clone
4C4.1, monoclonal
species reactivity
human
technique(s)
western blot: suitable
isotype
IgG1κ
NCBI accession no.
UniProt accession no.
shipped in
wet ice
target post-translational modification
unmodified
Gene Information
human ... PTHLH(5744)
General description
Immunogen
Application
Physical form
Analysis Note
Western Blotting Analysis: 2.0 µg/mL of this antibody detected PTHrP in 10 µg of MCF-7 cell lysate.
Other Notes
1 of 1
Dieser Artikel | |||
|---|---|---|---|
| antibody form purified immunoglobulin | antibody form affinity isolated antibody | antibody form affinity isolated antibody | antibody form ascites fluid |
| clone 4C4.1, monoclonal | clone polyclonal | clone polyclonal | clone 1ML-1D7, monoclonal |
| conjugate unconjugated | conjugate unconjugated | conjugate unconjugated | conjugate unconjugated |
| Gene Information human ... PTHLH(5744) | Gene Information human ... PTH(5741) | Gene Information human ... PTH1R(5745) | Gene Information human ... GHRL(51738) |
| species reactivity human | species reactivity human | species reactivity rat, mouse, human | species reactivity mouse, human |
| biological source mouse | biological source rabbit | biological source rabbit | biological source mouse |
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Lagerklasse
12 - Non Combustible Liquids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
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Verwandter Inhalt
A major focus of breast cancer research is to understand the mechanisms responsible for disease progression and drug resistance. Toward that end, it has been found that approximately two thirds of all human breast carcinomas overexpress the Estrogen Receptor α (ERα) protein and it remains the primary pharmacological target for endocrine therapy1,2. The normal cellular function of ERα is as a transcription factor that mediates a wide variety of physiological processes, many of which are dependent upon phosphorylation of the receptor at specific amino acid residues3,4. Indeed, ERα is known to be phosphorylated at a multitude of different sites, yet how these all correlate to disease remains unclear5. Here, we interrogated multiple sites of ERα for phosphorylation status by screening an extensive panel of different breast cancer patient samples and other non-breast cancer tissue microarray (TMA) slide samples to determine their relevance to disease.
Global Trade Item Number
| SKU | GTIN |
|---|---|
| MABC532 | 04055977177039 |