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MAB352

Anti-Serotonin Antibody, clone YC5/45

culture supernatant, clone YC5/45, Chemicon®

Synonym(e):

5-HT

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PackungsgrößeSKUVerfügbarkeitPreis
100 μL
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€ 300,00

Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
YC5/45, monoclonal
Species reactivity:
mouse, human, rat, lizard, rabbit, pig
Application:
IHC
Citations:
55

€ 300,00


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biological source

rat

Quality Level

antibody form

culture supernatant

antibody product type

primary antibodies

clone

YC5/45, monoclonal

species reactivity

mouse, human, rat, lizard, rabbit, pig

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable

isotype

IgG

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... HTR1A(3350)

Immunogen

Serotonin conjugated to BSA.

Application

Anti-Serotonin Antibody, clone YC5/45 is an antibody against Serotonin for use in IH.
Immunohistochemistry at 1:100-1:200 for formaldehyde fixed tissue.

Optimal working dilutions must be determined by the end user.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors

Biochem/physiol Actions

Recognizes the formaldehyde conjugate of serotonin. Without paraformaldehyde treatment, it cross-reacts in liquid phase with dopamine and tryptamine in hemagglutination tests. Shows no reactivity with catecholamine-containing neurons in formaldehyde fixed preparations. MAB352 reacts with serotonin in neurons and recognizes serotonergic sites in fixed tissue sections. By cell agglutination, no cross reactivity with 5-hydroxyindolacetic acid, GABA, noradrenaline, 5-hydroxytryptophan, carnosine or melatonin.

Physical form

Lyophilized Supernatant, preservative free.
Unpurified

Preparation Note

Lyophilized antibody can be kept at 2-8°C for up to 3 months and should be kept at -20°C for long term storage. Reconstitute with 100μL sterile DI water. Maintain at -20°C in undiluted aliquots for up to 12 months. Avoid repeated freeze-thaw cycles.

Analysis Note

Control
Brain tissue

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel
MAB11041MAB5598SAB4501470
Gene Information

human ... HTR1A(3350)

Gene Information

human ... HTR1A(3350)
rat ... Htr1A(24473)

Gene Information

mouse ... Hcn3(15168)

Gene Information

human ... HTR1B(3351)

biological source

rat

biological source

mouse

biological source

rat

biological source

rabbit

clone

YC5/45, monoclonal

clone

19A9.2, monoclonal

clone

TLL 6C5, monoclonal

clone

polyclonal

species reactivity

mouse, human, rat, lizard, rabbit, pig

species reactivity

human, rat

species reactivity

mouse, rat

species reactivity

human, mouse, rat

antibody form

culture supernatant

antibody form

purified immunoglobulin

antibody form

culture supernatant

antibody form

affinity isolated antibody

shipped in

dry ice

shipped in

wet ice

shipped in

dry ice

shipped in

wet ice


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pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2

Lagerklasse

11 - Combustible Solids

wgk

WGK 2



Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Alexander Drobyshevsky et al.
Journal of neurochemistry, 132(4), 394-402 (2014-11-26)
We hypothesized that a deficiency in the descending serotonergic input to spinal cord may underlie postnatal muscle hypertonia after global antenatal hypoxic-ischemic injury in a rabbit model of cerebral palsy. Neurotransmitter content was determined by HPLC in the spinal cord
Tanimul Alam et al.
Nature communications, 7, 10388-10388 (2016-01-23)
The molecular mechanisms underlying the ability of axons to regenerate after injury remain poorly understood. Here we show that in Caenorhabditis elegans, axotomy induces ectopic expression of serotonin (5-HT) in axotomized non-serotonergic neurons via HIF-1, a hypoxia-inducible transcription factor, and
Basudha Basu et al.
Reproduction (Cambridge, England), 135(5), 657-669 (2008-02-29)
Serotonin is reported to be present in early embryos of many species and plays an important role in early patterning. Since it is a fluorophore, it can be directly visualized using fluorescence microscopy. Here, we use three-photon microscopy to image



Global Trade Item Number

SKUGTIN
MAB35204053252360503

Questions

  1. MAB352 Is this a mouse monoclonal Ab? I see Rat in the source which is unusual for me. What secondary is ideal

    1 answer
    1. This product is a rat monoclonal Antibody. An anti-rat secondary antibody would be suitable. Please see the link below to review examples of anti-rat secondary antibodies:
      https://www.sigmaaldrich.com/US/en/search/anti-rat-antibody?facet=facet_product_category%3Asecondary%20antibodies&focus=products&page=1&perpage=30&sort=relevance&term=anti-rat%20antibody&type=product

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