EZGLP2

Rat/Human GLP-2 ELISA Kit

detects GLP-2 in 50 μL serum, plasma or cell culture supernatent

• Synonym(e): Glucagon-like peptide-2
• UNSPSC Code: 12161503
• eCl@ss: 32161000
• NACRES: NA.32
• Input: sample type plasma (K2 EDTA); sample type serum
• Species reactivity: human, rat
• Storage temp.: 2-8°C
• Shipped in: wet ice

Eigenschaften

• Produktname: GLP-2 ELISA, This GLP-2 ELISA is used to measure & quantify GLP-2 levels in Metabolism & Endocrine research.
• Quality Segment: 200
• species reactivity: human, rat
• packaging: kit of 1 × 96 wells
• parameter: 50 μL sample volume (4hr assay)
• technique(s): ELISA: suitable
• input: sample type plasma (K2 EDTA); sample type serum
• application(s): research use
• assay range: accuracy: 75-97%; (Human), accuracy: 94-109%; (Rat), sensitivity: 1 ng/mL; (50 μl sample size), standard curve range: 1-64 ng/mL, inter-assay cv: <12%; intra-assay cv: <10%
• detection method: colorimetric (450nm/590nm)
• shipped in: wet ice
• storage temp.: 2-8°C

Beschreibung

General description

The glucagon-like peptides GLP-1 and GLP-2 are important gut hormones released from the small intestine upon nutrient ingestion. In circulation, GLP-2 is present in two molecular forms, GLP-2 (1-33) and GLP-2 (3-33). Similar to GLP-1, active form GLP-2 (1-33) is cleaved to inactive form GLP-2 (3-33) by protease DPPIV. GLP-2 has been shown to play important roles in the regulation of gastrointestinal functions (digestion, absorption, motility, epithelial growth, and blood flow) and bone resorption. Thus, GLP-2 or its analogs may have therapeutic potentials for the treatment of diseases such as Crohn’s disease and osteoporosis.

Application

Research Category
Metabolism

Research Sub Category
Osteoporosis

This assay requires 50 µl of rat or human samples and is performed at room temperature as a 4 hour assay. GLP-2 has also been detected in guinea pig, horse, porcine, and non-human primate samples.

Used to detect/quantify: GLP-2

Biochem/physiol Actions

Human GLP-2 1-33 100%
Human GLP-2 3-33 112%
Rat GLP-2 101%

Other Notes

Please contact Technical Service for linearity of dilution.

Disclaimer

For research use only. Not for use in diagnostic procedures.

Sicherheitshinweise

• pictograms: GHS06,GHS05,GHS09
• signalword: Danger
• hcodes: H290,H302 + H332,H311,H317,H319,H335,H411
• pcodes: P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Met. Corr. 1 - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3