DX0830

Dichlormethan

Biosynthesis OmniSolv^®

• Synonym(e): Methylene Chloride, FM approval, Methylenchlorid
• Empirische Formel (Hill-System): CH₂Cl₂
• CAS-Nummer: 75-09-2
• Molekulargewicht: 84.93
• EC Index Number: 200-838-9
• UNSPSC Code: 12352101
• Beilstein/REAXYS Number: 1730800
• MDL number: MFCD00000881
• Assay: ≥99.9% (GC)
• Bp: 39.8-40 °C (lit.)
• Vapor pressure: 24.45 psi ( 55 °C), 6.83 psi ( 20 °C)

Eigenschaften

• vapor density: 2.9 (vs air)
• Quality Segment: 200
• vapor pressure: 24.45 psi ( 55 °C), 6.83 psi ( 20 °C)
• assay: ≥99.9% (GC)
• form: liquid
• autoignition temp.: 1223 °F
• expl. lim.: 22 %
• dilution: (for synthesis)
• impurities: ≤0.3 μeq/g Titrable acid, ≤1 ppm Halogen (as Cl), ≤30 ppm Water (H₂O)
• evapn. residue: ≤1 ppm
• color: APHA: ≤10
• refractive index: n20/D 1.424 (lit.)
• pH: 7 (20 °C)
• bp: 39.8-40 °C (lit.)
• mp: -95 °C, −95 °C (lit.)
• solubility: 20 g/L
• density: 1.325 g/mL at 25 °C (lit.)
• UV cutoff: ≤231 nm
• UV absorption: λ: 231 nm A_max: ≤1.00, λ: 240 nm A_max: ≤0.20, λ: 250 nm A_max: ≤0.01, λ: 270 nm A_max: ≤0.005
• shipped in: ambient
• storage temp.: room temp
• SMILES string: ClCCl
• InChI: 1S/CH2Cl2/c2-1-3/h1H2
• InChI key: YMWUJEATGCHHMB-UHFFFAOYSA-N

Beschreibung

General description

Dichloromethane is a volatile solvent specifically formulated for use in high-performance liquid chromatography (HPLC) and various analytical applications. Its low viscosity and strong solvating ability make it an excellent choice for extracting and purifying organic compounds in biosynthesis processes.

Application

Dichloromethane can be used as a:

• Solvent for the extraction of natural products and metabolites from biological samples, facilitating the analysis of compounds derived from biosynthetic pathways.
• Mobile phase in high-performance liquid chromatography (HPLC) is used for the separation and characterization of biosynthetic compounds and their derivatives.
• Recrystallization solvent for purifying active pharmaceutical ingredients (APIs) synthesized through biological methods, enhancing the quality and yield of the final product.

Packaging

M-Bottle for Solvents
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is packaged in 4L amber glass bottle

Preparation Note

Product filtered through a 0.2 μm filter

Analysis Note

Assay (GC)99.9% minColor (APHA)10 maxEvaporation residue1ppm maxFiltered through 0.2 µm filterTo pass testFluorescence (as quinine base)500ppt maxFormClear liquidHalogen (as Cl)1ppm maxInfrared SpectrumConforms to standardTitrable acid0.3µeq/g maxUV Abs. at 231 nm1.00AU maxUV Abs. at 240 nm0.20AU maxUV Abs. at 250 nm0.01AU maxUV Abs. at 270 nm0.005AU maxUV Cut-off231nm maxWater (H2O)30ppm max

Evaporation Number: 1.9

Legal Information

OMNISOLV is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H315,H319,H336,H351
• pcodes: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Central nervous system
• Lagerklasse: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• wgk: WGK 2