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Merck

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AB5380

Anti-Stickstoffmonoxid-Synthase-I-Antikörper

serum, Chemicon®

Synonym(e):

NOS I, bNOS, nNOS

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PackungsgrößeSKUVerfügbarkeitPreis
50 μL
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€ 491,00

Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
85

€ 491,00


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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

mouse, sheep, rat, human, monkey

manufacturer/tradename

Chemicon®

technique(s)

immunohistochemistry: suitable, western blot: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... NOS1(4842)

General description

161 kDa

Immunogen

Rekombinante humane neuronale Stickstoffmonoxid-Synthase.

Application

Dieser Anti-Stickoxid-Synthase-I-Antikörper ist zur Verwendung in IH und WB für den Nachweis von Stickoxid-Synthase I validiert.
Forschungskategorie
Neurowissenschaft
Forschungsunterkategorie
Oxidativer Stress
Western Blotting: 1:1.000–1:3.000 (ECL).

Immunhistochemie: 1:1.000–1:2.000 (ABC).

Optimale Arbeitsverdünnungen müssen vom Endanwender bestimmt werden.

Biochem/physiol Actions

Erkennt neuronale Stickstoffmonoxid-Synthase (nNOS, NOS-I, bNOS). Keine Kreuzreaktion mit iNOS und eNOS mittels Immunhistochemie.

Physical form

Kaninchenserum. Flüssigkeit mit 0,05% Natriumazid.
Nicht aufgereinigt

Preparation Note

Bei -20 °C ab Versanddatum 6 Monate haltbar. Aliquotieren, um wiederholtes Einfrieren und Auftauen zu vermeiden. Für maximale Produktrückgewinnung das Originalfläschchen nach dem Auftauen und vor dem Abnehmen der Kappe zentrifugieren.

Analysis Note

Kontrolle
Hirngewebe

Other Notes

Ersetzt: AB1552
Konzentration: Die chargenspezifische Konzentration entnehmen Sie bitte dem Analysenzertifikat.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Sofern in unserem Katalog oder anderen Begleitdokumenten unserer Produkte nicht anders angegeben, sind unsere Produkte nur für Forschungszwecke vorgesehen und nicht für andere Zwecke zu verwenden, einschließlich, jedoch nicht beschränkt auf unautorisierte kommerzielle Verwendung, zur In-vitro-Diagnostik, für Ex-vivo- oder In-vivo-Therapiezwecke oder jegliche Art der Einnahme oder Anwendung bei Menschen oder Tieren.

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Dieser Artikel
N218SAB4301472SAB4502010
biological source

rabbit

biological source

mouse

biological source

rabbit

biological source

rabbit

Quality Level

100

Quality Level

200

Quality Level

-

Quality Level

100

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

unconjugated

antibody form

serum

antibody form

ascites fluid

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

clone

polyclonal

clone

NOS-3F7-B11-B5, monoclonal

clone

polyclonal

clone

polyclonal

Gene Information

human ... NOS1(4842)

Gene Information

mouse ... Nos1(18125)
rat ... Nos1(24598)

Gene Information

human ... NOS1(4842)

Gene Information

human ... NOS1(4842)


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Lagerklasse

10 - Combustible liquids

wgk

WGK 1



Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Verwandter Inhalt

"Redox reactions are powerful chemical processes that involve the reduction and oxidation of proteins and metabolites found in living things. The mechanisms that regulate them are key to maintaining homeostasis and the balance between good health and disease pathology. Oxidative stress is the state where the delicate balance of redox biology is upset, and the pathology of oxidative stress are the cellular consequences to such an imbalance."

"Aging: getting older, exhibiting the signs of age, the decline in the physical (and mental) well-being over time, leading to death. Since the beginning of time, man has been obsessed with trying to slow down, stop, or even reverse the signs of aging. Many have gone as far as experimenting with nutritional regimens, eccentric exercises, fantastic rituals, and naturally occurring or synthetic wonder-elements to evade the signs of normal aging. Biologically speaking, what is aging? And what does the latest research tell us about the possibility of discovering the elusive “fountain of youth”? Many advances in our understanding of aging have come from systematic scientific research, and perhaps it holds the key to immortality. Scientifically, aging can be defined as a systems-wide decline in organismal function that occurs over time. This decline occurs as a result of numerous events in the organism, and these events can be classified into nine “hallmarks” of aging, as proposed by López-Otin et al. (2013). Several of the pathologies associated with aging are a direct result of these events going to extremes and may also involve aberrant activation of proliferation signals or hyperactivity. The hallmarks of aging have been defined based on their fulfillment of specific aging related criteria, such as manifestation during normal aging, acceleration of aging if experimentally induced or aggravated, and retardation of aging if prevented or blocked, resulting in increased lifespan. The nine hallmarks of aging are genomic instability, telomere attrition, epigenetic alterations, loss of proteostasis, deregulated nutrient sensing, mitochondrial dysfunction, cellular senescence, stem cell exhaustion, and altered intercellular communication. The biological processes underlying aging are complex. By understanding the hallmarks in greater detail, we can get closer to developing intervention strategies that can make the aging process less of a decline, and more of a recline."


Gaetano Scala et al.
Anatomical record (Hoboken, N.J. : 2007), 290(11), 1399-1412 (2007-10-12)
Choroid plexuses (CPs) play pivotal roles in many processes that establish, survey, and maintain the biochemical and cellular status of the central nervous system (CNS). Changes in the anatomy and physiology of CPs have been linked to several CNS diseases.
Yong Hwan Kwon et al.
PloS one, 12(1), e0169113-e0169113 (2017-01-04)
The gastric accommodation reflex is an important mechanism in gastric physiology. However, the aging-associated structural and functional changes in gastric relaxation have not yet been established. Thus, we evaluated the molecular changes of interstitial cell of Cajal (ICC) and neuronal
Sun Min Lee et al.
Journal of neurogastroenterology and motility, 23(4), 592-605 (2017-08-05)
Neuronal degeneration and changes in interstitial cells of Cajal (ICCs) are important mechanisms of age-related constipation. This study aims to compare the distribution of ICCs and neuronal nitric oxide synthase (nNOS) with regard to age-related changes between the ascending colon



Global Trade Item Number

SKUGTIN
AB538004053252468889

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