8.53029

Boc-Glu(OcHx)-OH

Novabiochem^®

• Synonym(e): Boc-Glu(OcHx)-OH, N-α-t.-Boc-L-glutamic acid γ-cyclohexyl ester
• Empirische Formel (Hill-System): C₁₆H₂₇NO₆
• CAS-Nummer: 73821-97-3
• Molekulargewicht: 329.39
• MDL number: MFCD00065570
• UNSPSC Code: 12352209
• NACRES: NA.22

Eigenschaften

• Quality Level: 200
• product line: Novabiochem^®
• assay: ≥98% (TLC)
• form: powder
• reaction suitability: reaction type: Boc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 54-57 °C
• application(s): peptide synthesis
• functional group: carboxylic acid
• storage temp.: 2-30°C
• SMILES string: N([C@@H](CCC(=O)OC1CCCCC1)C(=O)O)C(=O)OC(C)(C)C
• InChI: 1S/C16H27NO6/c1-16(2,3)23-15(21)17-12(14(19)20)9-10-13(18)22-11-7-5-4-6-8-11/h11-12H,4-10H2,1-3H3,(H,17,21)(H,19,20)/t12-/m0/s1
• InChI key: FDNMLANBNJDIRG-LBPRGKRZSA-N

Beschreibung

General description

Standard building block for introduction of glutamic acid in Boc SPPS. This side-chain protecting group for glutamic acid is used to minimize side reactions during acidic and basic treatments ^[1].

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Boc SPPS

Literature references

^[1] J. P. Tam, et al. (1979) Tetrahedron Lett., 42, 4033.

Analysis Note

Colour (visual): white to slight yellow to beige
Appearance of substance (visual): powder
Identity (IR): passes test
Optical rotation α 25/D (c=1 in methanol): -9.0 - -7.0 °
Purity (TLC(0811)): ≥ 98 %
Purity (DC (0157)): ≥ 98 %
Solubility (1 mmole in 2 ml DMF): clearly soluble

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-0121

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable