8.52033

Fmoc-Hyp-OH

Novabiochem^®

• Synonym(e): Fmoc-Hyp-OH, N-α-Fmoc-L-trans-4-hydroxyproline
• Empirische Formel (Hill-System): C₂₀H₁₉NO₅
• CAS-Nummer: 88050-17-3
• Molekulargewicht: 353.37
• UNSPSC Code: 12352209
• NACRES: NA.22
• MDL number: MFCD00151929

Eigenschaften

• Quality Level: 200
• product line: Novabiochem^®
• assay: ≥95.0% (acidimetric), ≥98% (TLC), ≥98.0% (HPLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• mp: 189 °C
• application(s): peptide synthesis
• functional group: hydroxyl
• storage temp.: 2-30°C
• SMILES string: N4([C@@H](C[C@H](C4)O)C(=O)O)C(=O)OCC1c2c(cccc2)c3c1cccc3
• InChI: 1S/C20H19NO5/c22-12-9-18(19(23)24)21(10-12)20(25)26-11-17-15-7-3-1-5-13(15)14-6-2-4-8-16(14)17/h1-8,12,17-18,22H,9-11H2,(H,23,24)/t12-,18+/m1/s1
• InChI key: GOUUPUICWUFXPM-XIKOKIGWSA-N

Beschreibung

General description

Building block for introduction of hydroxyproline amino-acid residues by Fmoc SPPS

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS

Analysis Note

Color (visual): white to yellow to brown
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(011A)): ≥ 98 %
Purity (TLC(0811)): ≥ 98 %
Assay (HPLC, area%): ≥ 98.0 % (a/a)
Solubility (1 mmole in 2 ml DMF): clearly soluble
Assay (acidimetric): ≥ 95.0 %
Water (K. F.): ≤ 1.00 %

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Other Notes

Replaces: 04-12-1068

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable