539142

Proteasom-Substrat III, fluorogen

≥98% (HPLC), amorphous solid, proteasome substrate, Calbiochem^®

• Synonym(e): Proteasom-Substrat III, fluorogen
• Empirische Formel (Hill-System): C₄₀H₅₃N₅O₁₀
• Molekulargewicht: 763.88
• UNSPSC Code: 12352200
• NACRES: NA.77
• Assay: ≥98% (HPLC)
• Form: amorphous solid
• Quality level: 100
• Storage condition: OK to freeze, protect from light

Eigenschaften

• Produktname: Proteasom-Substrat III, fluorogen, Proteasome Substrate III, Fluorogenic, is a substrate for proteasome. Also acts as a substrate for calpain, chymotrypsin, and ingensin.
• Quality Level: 100
• assay: ≥98% (HPLC)
• form: amorphous solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze, protect from light
• color: white
• solubility: DMSO: 50 mg/mL
• fluorescence: λ_ex ~380 nm, λ_em ~460 nm
• shipped in: ambient
• storage temp.: −20°C

Beschreibung

General description

Fluorogenes Proteasomsubstrat. Dient auch als Substrat für Calpain, Chymotrypsin und Ingensin.

Biochem/physiol Actions

Hemmt Serin- und Cysteinproteasen.

Primärziel
Proteasom

Produkt konkurriert nicht mit ATP.

Reversibel: nein

Zellpermeabel: nein

Preparation Note

Nach der Rekonstitution in Aliquote aufteilen und einfrieren (-20 °;C). Stammlösungen sind bei -20 °;C bis zu 6 Monate haltbar.

Other Notes

Anderson, M., et al. 1999. Exp. Eye Res.69, 129.
Rock, K.L., et al. 1994. Cell 78, 761.
Tsubuki, S., et al. 1993. Biochem. Biophys. Res. Commun.196, 1195.
Sasaki, T., et al. 1984. J. Biol. Chem. 259, 12489.

Suc-Leu-Leu-Val-Tyr-AMC

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxizität: Standard-Handhabung (A)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable