368057

Granzyme B Substrate I, Colorimetric

Colorimetric substrate for the detection of granzyme B and caspase-8 activity.

• Synonym(e): Granzyme B Substrate I, Colorimetric, Ac-IETD- pNA, Caspase-8 Substrate I, Ac-IETD-pNA, Caspase-8 Substrate I
• Empirische Formel (Hill-System): C₂₇H₃₈N₆O₁₂
• Molekulargewicht: 638.62
• UNSPSC-Code: 12352200
• NACRES: NA.77

Eigenschaften

• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Form: lyophilized solid
• Hersteller/Markenname: Calbiochem^®
• Lagerbedingungen: OK to freeze; protect from light
• Farbe: white
• Löslichkeit: DMSO: 5 mg/mL
• Versandbedingung: ambient
• Lagertemp.: −20°C

Beschreibung

Allgemeine Beschreibung

Colorimetric substrate for detection of granzyme B. Cleavage is monitored colorimetrically at ~405 nm.

Colorimetric substrate for the detection of granzyme B and caspase-8 activity. Cleavage of pNA is monitored colorimetrically at ~405 nm.

Biochem./physiol. Wirkung

Cell permeable: no

Primary Target
Colorimetric substrate for the detection of granzyme B and caspase-8 activity

Product does not compete with ATP.

Reversible: no

Warnhinweis

Toxicity: Standard Handling (A)

Sequenz

Ac-Ile-Glu-Thr-Asp-pNA

Rekonstituierung

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Sonstige Hinweise

Koeplinger, K.A., et al. 2000. Protein Exp. Purif. 18, 378.

Rechtliche Hinweise

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable