345250

N-Acetyllactosamine

A substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar.

• Synonym(e): N-Acetyllactosamine, O-β-D-Galactopyranosyl-β1,4-2-acetamido-2-deoxy-D-glucose, Galβ1,4GlcNAc, LacNAc
• Empirische Formel (Hill-System): C₁₄H₂₅NO₁₁
• CAS-Nummer: 32181-59-2
• Molekulargewicht: 383.35
• UNSPSC Code: 12352201
• NACRES: NA.79
• MDL number: MFCD00063785

Eigenschaften

• Quality Segment: 100
• form: solid
• manufacturer/tradename: Calbiochem^®
• storage condition: OK to freeze
• color: white to off-white
• solubility: water: 5 mg/mL
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: N([C@H]1[C@@H](O[C@@H]([C@H]([C@@H]1O)O[C@@H]2O[C@@H]([C@@H]([C@@H]([C@H]2O)O)O)CO)CO)O)C(=O)C
• InChI: 1S/C14H25NO11/c1-4(18)15-7-9(20)12(6(3-17)24-13(7)23)26-14-11(22)10(21)8(19)5(2-16)25-14/h5-14,16-17,19-23H,2-3H2,1H3,(H,15,18)/t5-,6-,7-,8+,9-,10+,11-,12-,13-,14+/m1/s1
• InChI key: KFEUJDWYNGMDBV-LODBTCKLSA-N

Beschreibung

General description

A substrate for galactosidases, fucosyltransferases, and sialyltransferases. Useful as a lectin inhibitory sugar.

Application

• Mass Spectrometry Analysis of Glycopeptides Enriched by Anion Exchange-Mediated Methods Reveals PolyLacNAc-Extended N-Glycans in Integrins and Tetraspanins in Melanoma Cells.: This research demonstrates the application of mass spectrometry in identifying N-acetyllactosamine extensions on glycoproteins in melanoma cells, providing insights into cellular adhesion and signaling mechanisms (Čaval et al., 2024).

Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.

Analysis Note

Single spot by TLC

Other Notes

Gunnarsson, A., et al. 1984. Infect. Immun.45, 41.
Loomes, L.M., et al. 1984. Nature307, 560.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Toxicity: Standard Handling (A)

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable