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33-016

PI 3-Kinase HTRF® Assay; 384 wells

The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 1 plate.

Synonym(e):

Assay for PI 3-Kinase, HTRF Assay, PI 3-Kinase Assay

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UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000
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Quality Level

100

species reactivity

human, mouse

manufacturer/tradename

HTRF®, Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

NM_006218.2

UniProt accession no.

P42336

detection method

fluorometric (HTRF)

shipped in

dry ice

Gene Information

human ... PIK3CA(5290)

Application

Used to detect/quantify: PI 3-Kinase

Biochem/physiol Actions

Target Sub-Family: PI3K/PI4K

Packaging

Kit capacity: 384 wells

Other Notes

4X Reaction Buffer

PIP2 (Substrate; 1mM stock)

Stop Reagent A

Stop Reagent B

DM A Detection Reagent

DM B Detection Reagent

DM C Detection Reagent

Legal Information

HTRF is a registered trademark of Cis Bio International
UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel
33-03733-01733-036
PI 3-Kinase HTRF® Assay; 384 wells The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 1 plate.

Sigma-Aldrich

33-016

PI 3-Kinase HTRF® Assay; 384 wells

PI 3-Kinase HTRF® Assay; 50,000 wells The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 50,000 wells.

Sigma-Aldrich

33-037

PI 3-Kinase HTRF® Assay; 50,000 wells

PI 3-Kinase HTRF® Assay; 1920 wells The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 5 plates.

Sigma-Aldrich

33-017

PI 3-Kinase HTRF® Assay; 1920 wells

PI 3-Kinase HTRF® Assay; 10,000 wells The PI 3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for testing all Class I PI3-Kinases in a homogeneous format. This pack size has a screening capacity of 10,000 wells.

Sigma-Aldrich

33-036

PI 3-Kinase HTRF® Assay; 10,000 wells

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

technique(s)

activity assay: suitable (kinase)

Gene Information

human ... PIK3CA(5290)

Gene Information

human ... PIK3CA(5290)

Gene Information

human ... PIK3CA(5290)

Gene Information

human ... PIK3CA(5290)

species reactivity

human, mouse

species reactivity

human, mouse

species reactivity

mouse, human

species reactivity

mouse, human

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

detection method

fluorometric (HTRF)

detection method

fluorometric (HTRF)

detection method

fluorometric (HTRF)

detection method

fluorometric (HTRF)

NCBI accession no.

NM_006218.2

NCBI accession no.

NM_006218.2

NCBI accession no.

NM_006218.2

NCBI accession no.

NM_006218.2

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H319

Hazard Classifications

Eye Irrit. 2

Lagerklasse

10 - Combustible liquids

wgk

WGK 2

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Verwandter Inhalt

Unlocking the Mystery of Cancer: Do the Mutant p110α Subunits of PI3-Kinase Hold the Key?

This paper provides an overview of PI3-kinase and what makes them unique, their implications for cancer, their roles in signal transduction and the challenges researchers face today with advancing this reserach.

PI 3-Kinase HTRF Assay

Complete PI3-Kinase Assay Solution The PI3-Kinase HTRF Assay is a high-performance assay kit that provides a universal method for assaying all Class I PI3-Kinases in a homogeneous 384 well format. Nowhere else will you find a kit that offers this level of performance. And, nowhere else you will find as many Class I PI3-Kinases available.

Advancing cancer research: From hallmarks & biomarkers to tumor microenvironment progression

"Recognizing both the tremendous opportunities and the challenges facing cancer research, we are dedicated to developing and refining tools and technologies for the study of cancer. With our comprehensive portfolio, including the Upstate®, Chemicon®, and Calbiochem® brands of reagents and antibodies, researchers can count on dependable, high quality solutions for analyzing all the hallmarks of cancer."

Alle verwandten Inhalte anzeigen
James M J Dickson et al.
Bioscience reports, 33(6) (2013-08-24)
NTT (N-terminal tags) on the catalytic (p110) sub-unit of PI 3-K (phosphoinositol 3-kinase) have previously been shown to increase cell signalling and oncogenic transformation. Here we test the impact of an NT (N-terminal) His-tag on in vitro lipid and protein
Christina M Buchanan et al.
PloS one, 8(8), e71337-e71337 (2013-08-13)
In addition to lipid kinase activity, the class-I PI 3-kinases also function as protein kinases targeting regulatory autophosphorylation sites and exogenous substrates. The latter include a recently identified regulatory phosphorylation of the GM-CSF/IL-3 βc receptor contributing to survival of acute
Stephen Jamieson et al.
The Biochemical journal, 438(1), 53-62 (2011-06-15)
Genetic alterations in PI3K (phosphoinositide 3-kinase) signalling are common in cancer and include deletions in PTEN (phosphatase and tensin homologue deleted on chromosome 10), amplifications of PIK3CA and mutations in two distinct regions of the PIK3CA gene. This suggests drugs
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Global Trade Item Number

SKUGTIN
33-01604053252470806

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