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14-253-M

p38β2/SAPK2b2 Protein, active, 10 µg

Active, N-terminal GST fusion protein corresponding to full length human p38β2/SAPK2b2 activated with MKK6. For use in Kinase Assays.

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Über diesen Artikel

UNSPSC Code:
12352202
NACRES:
NA.32
eCl@ss:
32160405
Biological source:
human
Mol wt:
Mw 71 kDa


biological source

human

Quality Level

mol wt

Mw 71 kDa

manufacturer/tradename

Upstate®

technique(s)

activity assay: suitable (kinase)

NCBI accession no.

UniProt accession no.

General description

N-terminal GST fusion protein corresponding to full length human p38β2/SAPK2b2 activated with MKK6.
Product Source: full length human p38β2/SAPK2b2, expressed in E. coli.

Biochem/physiol Actions

Protein Target: p38β2/SAPK2b2
Target Sub-Family: CMGC

Physical form

Affinity chromatography on glutathione-agarose beads

Preparation Note

6 months at -20°C

Analysis Note

routinely evaluated by phosphorylation of myelin basic protein

Other Notes

For Specific Activity data, refer to the Certificate of Analysis for individual lots of this enzyme.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


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Warning

hcodes

Hazard Classifications

Skin Sens. 1

Lagerklasse

10 - Combustible liquids

wgk

WGK 2



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A Cuenda et al.
The EMBO journal, 16(2), 295-305 (1997-01-15)
Stress-activated protein kinase-3 (SAPK3), a recently described MAP kinase family member with a wide-spread tissue distribution, was transfected into several mammalian cell lines and shown to be activated in response to cellular stresses, interleukin-1 (IL-1) and tumour necrosis factor (TNF)
A Cuenda et al.
FEBS letters, 364(2), 229-233 (1995-05-08)
A class of pyridinyl imidazoles inhibit the MAP kinase homologue, termed here reactivating kinase (RK) [Lee et al. (1994) Nature 372, 739-746]. We now show that one of these compounds (SB 203580) inhibits RK in vitro (IC50 = 0.6 microM)



Global Trade Item Number

SKUGTIN
14-25304053252468773

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