Yes, this product activity is measured as ≥ 0.70 FIP-U/mg. There is no conversion factor for FIP to other units, the customer has to determine the conversion factor experimentally. The FIP unit is the measurement of enzymatic activity according to test methods of the Federation Internationale Pharmaceutique. One FIP Unit of pepsin is expressed as micromoles of porcine gastric mucosa equivalents liberated per minute at 25°C.
1.07185
Pepsin
(from porcine gastric mucosa) 0.7 FIP-U/mg for biochemistry EC 3.4.23.1
Synonym(e):
Pepsin
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Über diesen Artikel
CAS-Nummer:
Molekulargewicht:
35000
EC Index Number:
232-629-3
NACRES:
NA.21
MDL number:
UNSPSC Code:
12352204
eCl@ss:
42010127
pH
4.0-5.0 (20 °C, 10 g/L in H2O)
solubility
10 g/L
bulk density
380‑420 kg/m3
storage temp.
2-30°C
Application
Pepsin has been used in the preparation of simulated gastric fluid to perform in vitro gastric digestion.
Biochem/physiol Actions
Pepsin is a component of gastric juice and is associated with protein digestion. It is an endopeptidase that catalyzes the degradation of proteins into peptides and amino acids for small intestinal absorption. Pepsin is released as a zymogen (pepsinogen) by the chief cells of the gastric lining. It gets activated by the acidic environment created by the hydrochloric acid (HCl) of gastric juice. Pepsin is active at pH 1.5 to 2, in the stomach. It is involved in the conversion of food bolus into chyme. It is associated with laryngopharyngeal reflux (LPR) indicated by chronic cough, mild dysphagia, hoarseness, and non-productive throat clearing.
Analysis Note
Aussehen: feines, schwach gelbliches Pulver
Aktivität/FIP (Hämoglobin, pH 1.6, 25 °C): ≥ 0.70 FIP-U/mg
pH-Wert (1 %; Wasser): 4.0 - 5.0
Wasser (nach Karl Fischer): ≤ 6.0 %
Aktivität/FIP (Hämoglobin, pH 1.6, 25 °C): ≥ 0.70 FIP-U/mg
pH-Wert (1 %; Wasser): 4.0 - 5.0
Wasser (nach Karl Fischer): ≤ 6.0 %
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Danger
Hazard Classifications
Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - STOT SE 3
target_organs
Respiratory system
Lagerklasse
11 - Combustible Solids
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
hcodes
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Would I like to know is the lyophilized powder units/mg protein in this Pepsin
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