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Merck

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09-278

Anti-20S proteasome subunit β5 Antibody

serum, Upstate®

Synonym(e):

LMP17, MB1

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Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.77
eCl@ss:
32160702
Conjugate:
unconjugated
Clone:
polyclonal
Application:
IHC, WB
Citations:
5
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biological source

rabbit

Quality Level

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable, western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

unmodified

Gene Information

human ... PSMB5(5693)

General description

22 kDa

Immunogen

Peptide corresponding to residues 194-207 of human proteasome subunit β5 conjugated to KLH.

Application

Research Category
Protein Trafficking
Research Sub Category
Ubiquitin & Ubiquitin Metabolism
This Anti-20S proteasome subunit β5 Antibody is validated for use in IH, WB for the detection of 20S proteasome subunit β5.

Biochem/physiol Actions

Recognizes proteasome subunit β5

Physical form

100 µL of purified antiserum preparation in PBS containing 0.09% sodium azide. Dilute to working strength with phosphate buffered saline pH 7.2-7.4.
antiserum

Preparation Note

Stable for 1 year at -20°C from date of shipment for up to 12 months.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel
09-27907-121907-868
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

antibody form

serum

antibody form

serum

antibody form

affinity purified immunoglobulin

antibody form

affinity purified immunoglobulin

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

clone

polyclonal

clone

polyclonal

clone

polyclonal

clone

polyclonal

species reactivity

human

species reactivity

mouse, human, rabbit

species reactivity

mouse, bovine, human, rat

species reactivity

mouse

Gene Information

human ... PSMB5(5693)

Gene Information

human ... PSMB6(5694)

Gene Information

human ... PPP2CB(5516)

Gene Information

human ... PRKACB(5567)


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Lagerklasse

12 - Non Combustible Liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable



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Cyriel S Olie et al.
iScience, 12, 318-332 (2019-02-11)
Reduced poly(A)-binding protein nuclear 1 (PABPN1) levels cause aging-associated muscle wasting. PABPN1 is a multifunctional regulator of mRNA processing. To elucidate the molecular mechanisms causing PABPN1-mediated muscle wasting, we compared the transcriptome with the proteome in mouse muscles expressing short
K Tanaka et al.
Molecular biology reports, 24(1-2), 3-11 (1997-03-01)
The 26S proteasome is an eukaryotic ATP-dependent, dumbbell-shaped protease complex with a molecular mass of approximately 2000 kDa. It consists of a central 20S proteasome, functioning as a catalytic machine, and two large V-shaped terminal modules, having possible regulatory roles
Muhammad Riaz et al.
PLoS genetics, 12(5), e1006031-e1006031 (2016-05-07)
Poly(A) Binding Protein Nuclear 1 (PABPN1) is a multifunctional regulator of mRNA processing, and its expression levels specifically decline in aging muscles. An expansion mutation in PABPN1 is the genetic cause of oculopharyngeal muscle dystrophy (OPMD), a late onset and



Global Trade Item Number

SKUGTIN
09-27804053252329722

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