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07-344

Anti-CPI-17 Antibody

Name: Anti-CPI-17 Antibody
Brand: MM
Price: 478 EUR

Upstate^®, from rabbit

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Packungsgröße	SKU	Verfügbarkeit	Preis
200 μg		Warenkorb auf Verfügbarkeit prüfen	€ 478,00

Über diesen Artikel

UNSPSC Code:

12352203

NACRES:

NA.41

eCl@ss:

32160702

Conjugate:

unconjugated

Clone:

polyclonal

Application:

Citations:

€ 478,00

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Eigenschaften

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

purified antibody

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, pig, mouse, human, rabbit, bovine

manufacturer/tradename

Upstate^®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_033256

UniProt accession no.

Q96A00

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

bovine ... Ppp1R14A(615348)
human ... PPP1R14A(94274)
mouse ... Ppp1R14A(68458)
pig ... Ppp1R14A(397610)
rat ... Ppp1R14A(114004)

Beschreibung

General description

22kDa

Immunogen

Recombinant protein, full length pig CPI-17

Application

Anti-CPI-17 Antibody is an antibody against CPI-17 for use in WB.

NOT cross-reactive in yeast.

Research Category
Signaling

Research Sub Category
Cytoskeletal Signaling

Biochem/physiol Actions

CPI-17

Physical form

Format: Purified

PBS, 0.02% sodium azide before the addition of glycerol to 10%

Protein A chromatography

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot on RIPA lysates from mouse brain nuclear fraction and pig carotid artery tissue extract

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Dieser Artikel	36-006	SAB5500021	AB19027
Sigma-Aldrich 07-344 Anti-CPI-17 Antibody	Sigma-Aldrich 36-006 Anti-phospho-CPI-17 (Thr38) Antibody	Sigma-Aldrich SAB5500021 Anti-Cadherin -17 antibody, Rabbit monoclonal	Sigma-Aldrich AB19027 Anti-ADAM 17 Antibody
antibody form purified antibody	antibody form purified antibody	antibody form affinity isolated antibody	antibody form purified antibody
species reactivity rat, pig, mouse, human, rabbit, bovine	species reactivity rabbit, bovine, human, pig, mouse, rat	species reactivity human (tested)	species reactivity human, mouse
clone polyclonal	clone polyclonal	clone SP183, monoclonal	clone polyclonal
conjugate unconjugated	conjugate -	conjugate unconjugated	conjugate unconjugated
biological source rabbit	biological source rabbit	biological source rabbit	biological source rabbit
Gene Information bovine ... Ppp1R14A(615348) human ... PPP1R14A(94274) mouse ... Ppp1R14A(68458) pig ... Ppp1R14A(397610) rat ... Ppp1R14A(114004)	Gene Information bovine ... Ppp1R14A(615348) human ... PPP1R14A(94274) mouse ... Ppp1R14A(68458) pig ... Ppp1R14A(397610) rat ... Ppp1R14A(114004)	Gene Information human ... CDH17(1015)	Gene Information human ... ADAM17(6868)

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Lagerklasse

12 - Non Combustible Liquids

wgk

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Histamine-induced vasoconstriction involves phosphorylation of a specific inhibitor protein for myosin phosphatase by protein kinase C alpha and delta isoforms.

M Eto et al.

The Journal of biological chemistry, 276(31), 29072-29078 (2001-06-09)

Histamine stimulus triggers inhibition of myosin phosphatase-enhanced phosphorylation of myosin and contraction of vascular smooth muscle. In response to histamine stimulation of intact femoral artery, a smooth muscle-specific protein called CPI-17 (for protein kinase C-potentiated inhibitory protein for heterotrimeric myosin

Cerebellar long-term synaptic depression requires PKC-mediated activation of CPI-17, a myosin/moesin phosphatase inhibitor

Eto, M., et al

Neuron, 36, 1145-1158 (2002)

Solution NMR structure of the myosin phosphatase inhibitor protein CPI-17 shows phosphorylation-induced conformational changes responsible for activation.

Ohki, S, et al.

Journal of Molecular Biology, 314, 839-849 (2001)

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