Direkt zum Inhalt
Merck

Fortfahren mit

05-793

Anti-phospho-Estrogen Receptor alpha (Ser118) Antibody, clone NL44, rabbit monoclonal

clone NL44, Upstate®, from rabbit

Anmelden zur Ansicht der Organisations- und Vertragspreise.

Größe auswählen

Ansicht ändern
PackungsgrößeSKUVerfügbarkeitPreis
100 μL
Warenkorb auf Verfügbarkeit prüfen
€ 428,00

Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.41
eCl@ss:
32160702
Clone:
NL44, monoclonal
Species reactivity:
human
Application:
WB
Citations:
6

€ 428,00


Warenkorb auf Verfügbarkeit prüfen

Großbestellung anfragen
Technischer Dienst
Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.
Unterstützung erhalten


biological source

rabbit

Quality Segment

antibody form

purified antibody

antibody product type

primary antibodies

clone

NL44, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

UniProt accession no.

shipped in

dry ice

target post-translational modification

phosphorylation (pSer118)

Gene Information

human ... ESR1(2099)

General description

~66kDa

Immunogen

Peptide containing the sequence QLpSPF in which pS corresponds to phosphoserine at residue 118 of human estrogen receptor alpha

Application

Anti-phospho-Estrogen Receptor alpha (Ser118) Antibody, clone NL44 is a Rabbit Monoclonal Antibody for detection of ER alpha also known as Estrogen receptor alpha & has been tested in WB.
Research Category
Epigenetics & Nuclear Function
Research Sub Category
Transcription Factors

Biochem/physiol Actions

Predicted to cross-react with camel, mouse, pig and Syrian hamster based on sequence homology
phospho-estrogen receptor a (Ser118)

Physical form

0.2M Tris-glycine, pH 7.4, 0.15M NaCl, 100mM EDTA, 0.05% sodium azide, before the addition of glycerol to 30%
Format: Purified
Protein A purified

Preparation Note

2 years at -20°C

Analysis Note

routinely evaluated by immunoblot on RIPA lysates from MCF-7 cells treated with estradiol and EGF, and recombinant estrogen receptor alpha phosphorylated in vitro with MAP Kinase 2/Erk2, active (Catalog #14-173)

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Ähnliche Artikel vergleichen

Vollständigen Vergleich anzeigen

Unterschiede anzeigen

1 of 1

Dieser Artikel
07-66205-82404-824
Gene Information

human ... ESR1(2099)

Gene Information

human ... ESR1(2099)

Gene Information

human ... ESR2(2100)

Gene Information

human ... ESR2(2100)
mouse ... Esr2(13983)
rat ... Esr2(25149)

species reactivity

human

species reactivity

hamster, mouse, rat, human

species reactivity

human

species reactivity

mouse, rat, human

antibody form

purified antibody

antibody form

purified antibody

antibody form

purified immunoglobulin

antibody form

culture supernatant

biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

clone

NL44, monoclonal

clone

polyclonal

clone

68-4, monoclonal

clone

68-4, monoclonal

isotype

IgG

isotype

IgG

isotype

IgG

isotype

IgG


Still not finding the right product?

Probieren Sie unser Produkt-Auswahlhilfe, um Ihre Auswahl einzugrenzen


Lagerklasse

10 - Combustible liquids

wgk

WGK 1



Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen


Verwandter Inhalt

A major focus of breast cancer research is to understand the mechanisms responsible for disease progression and drug resistance. Toward that end, it has been found that approximately two thirds of all human breast carcinomas overexpress the Estrogen Receptor α (ERα) protein and it remains the primary pharmacological target for endocrine therapy1,2. The normal cellular function of ERα is as a transcription factor that mediates a wide variety of physiological processes, many of which are dependent upon phosphorylation of the receptor at specific amino acid residues3,4. Indeed, ERα is known to be phosphorylated at a multitude of different sites, yet how these all correlate to disease remains unclear5. Here, we interrogated multiple sites of ERα for phosphorylation status by screening an extensive panel of different breast cancer patient samples and other non-breast cancer tissue microarray (TMA) slide samples to determine their relevance to disease.






Global Trade Item Number

SKUGTIN
05-79304053252474477

Questions

Reviews

No rating value

Active Filters