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P178

Pyridoxal phosphate-6-azo(benzene-2,4-disulfonic acid) tetrasodium salt hydrate

solid, ≥98% (HPLC)

Sinónimos:

4-[[4-Formyl-5-hydroxy-6-methyl-3-[(phosphonooxy)methyl]-2-pyridinyl]azo]-1,3-benzenedisulfonic acid tetrasodium salt, PPADS tetrasodium salt hydrate

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Tamaño de envaseSKUDisponibilidadPrecio
50 mg
Comprobar disponibilidad del carrito
$439.000

Acerca de este artículo

Fórmula empírica (notación de Hill):
C14H10N3Na4O12PS2 · xH2O
Número CAS:
Peso molecular:
599.31 (anhydrous basis)
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352106
MDL number:
Assay:
≥98% (HPLC)
Form:
solid

$439.000


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Quality Level

assay

≥98% (HPLC)

form

solid

color

red to orange

solubility

H2O: >10 mg/mL

storage temp.

−20°C

SMILES string

O.[Na+].[Na+].[Na+].[Na+].Cc1nc(\N=N\c2ccc(cc2S([O-])(=O)=O)S([O-])(=O)=O)c(COP([O-])([O-])=O)c(C=O)c1O

InChI

1S/C14H14N3O12PS2.4Na.H2O/c1-7-13(19)9(5-18)10(6-29-30(20,21)22)14(15-7)17-16-11-3-2-8(31(23,24)25)4-12(11)32(26,27)28;;;;;/h2-5,19H,6H2,1H3,(H2,20,21,22)(H,23,24,25)(H,26,27,28);;;;;1H2/q;4*+1;/p-4/b17-16+;;;;;

InChI key

JTTDHFFNVGHDLN-YDTRVRFHSA-J

Biochem/physiol Actions

Non-selective P2 purinoceptor antagonist which blocks responses at both pre- and post-junctional sites.

Features and Benefits

This compound is featured on the P2 Receptors: P2X Ion Channel Family and P2 Receptors: P2Y G-Protein Family pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Disclaimer

Light sensitive

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Este artículo
N7505N163093219
assay

≥98% (HPLC)

assay

≥97% (HPLC), ≥97% (spectrophotometric assay)

assay

≥93% (HPLC), ≥93% (spectrophotometric assay)

assay

≥90% (HPLC)

Quality Level

100

Quality Level

300

Quality Level

300

Quality Level

100

solubility

H2O: >10 mg/mL

solubility

10 mM NaOH: soluble 50 mg/mL, clear

solubility

10 mM NaOH: soluble 50 mg/mL, clear

solubility

-

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

form

solid

form

powder

form

powder

form

solid

Gene Information

human ... LPAR4(2846), LTB4R(1241), P2RX1(5023), P2RY1(5028), P2RY10(27334), P2RY11(5032), P2RY12(64805), P2RY13(53829), P2RY14(9934), P2RY2(5029), P2RY4(5030), P2RY5(10161), P2RY6(5031), P2RY8(286530)

Gene Information

-

Gene Information

-

Gene Information

-


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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Marian T Namovic et al.
Current protocols in pharmacology, Chapter 9, Unit 9-Unit 9 (2012-06-12)
Adenosine triphosphate (ATP) activates two receptor superfamilies, metabotropic P2Y and ionotropic P2X receptors. The P2X receptors are nonselective cation channels that are widely expressed on excitable cells including neurons, glia, and smooth muscle cells. The protocols in this unit are
Christian Kranjec et al.
Scientific reports, 11(1), 13909-13909 (2021-07-08)
Bacteriocins are ribosomally-synthesized antimicrobial peptides, showing great potential as novel treatment options for multidrug-resistant pathogens. In this study, we designed a novel hybrid bacteriocin, Hybrid 1 (H1), by combing the N-terminal part and the C-terminal part of the related bacteriocins
G Lambrecht et al.
European journal of pharmacology, 217(2-3), 217-219 (1992-07-07)
We have characterized PPADS (pyridoxalphosphate-6-azophenyl-2',4'-disulfonic acid) as a novel antagonist which selectively blocks P2 purinoceptor-mediated responses in rabbit vas deferens at pre- and postjunctional sites. PPADS did not interact with alpha 1-adrenoceptors, muscarinic M2 and M3 receptors, histamine H1 and



Número de artículo de comercio global

SKUGTIN
P178-250MG04061832402215
P178-10MG04061834356646
P178-50MG04061834356653

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