E6511

Ethylendiamintetraessigsäure Tetranatriumsalz Dihydrat

BioReagent, suitable for cell culture, 98.5-102.0%

• Synonym(e): EDTA Tetranatriumsalz, Edathamil, Tetranatrium-Ethylendiamintetraacetat Dihydrat
• Lineare Formel: (NaOOCCH₂)₂NCH₂CH₂N(CH₂COONa)₂ · 2H₂O
• CAS-Nummer: 10378-23-1
• Molekulargewicht: 416.20
• UNSPSC Code: 12352204
• NACRES: NA.75
• PubChem Substance ID: 24894629
• EC Number: 200-573-9
• Beilstein/REAXYS Number: 3861753
• MDL number: MFCD00150026

Eigenschaften

• InChI: 1S/C10H16N2O8.4Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;;;2*1H2/q;4*+1;;/p-4
• InChI key: KSYNLCYTMRMCGG-UHFFFAOYSA-J
• SMILES string: O.O.[Na+].[Na+].[Na+].[Na+].[O-]C(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC([O-])=O
• product line: BioReagent
• assay: 98.5-102.0%
• form: powder
• technique(s): cell culture | mammalian: suitable
• solubility: H₂O: 160 mg/mL
• shipped in: ambient
• storage temp.: room temp
• Quality Level: 200

Beschreibung

General description

Ethylenediaminetetraacetic acid (EDTA) is a chelator of metal ions.[1] It is a substituted diamine, which has antibacterial activity. EDTA removes the undesirable effects of ferric, cupric and manganic ions in bleaching. It prevents cellular division, chlorophyll synthesis and algal biomass production.[2] EDTA is an inhibitor of metalloprotease.[1] It has anticoagulant property.[3]

Application

Ethylenediaminetetraacetic acid tetrasodium salt dihydrate has been used:

• as a chelating agent to isolate human endometrial stem cell/stromal cells (hEnSCs) from menstrual blood[4]
• as a chelator in animal and testicular cell isolation[5]
• as a chelator for the culture of neural stem cells[6]

Biochem/physiol Actions

Etyhlendiamintetraessigsäure (EDTA) wird zum Eliminieren der Enzymhemmung durch Schwermetallspuren sowie zur Hemmung von Enzymen, die zweiwertige Kationen als Cofaktoren benötigen verwendet.

Sicherheitshinweise

• pictograms: GHS08,GHS05,GHS07
• signalword: Danger
• hcodes: H302 + H332,H318,H373
• pcodes: P260 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 - P314
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Dam. 1 - STOT RE 2
• target_organs: Respiratory Tract
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves