49879

Neoandrographolid

analytical standard

• Synonym(e): ent-19-Hydroxy-8(17),13-labdadien-16,15-olid-19-O-β-D-glucopyranosid, D-Glucopyranosyloxy)-methyl]-decahydro-5,8a-dimethyl-2-methylen-1-naphthalinyl]-ethyl]-2(5H)-furanon
• Empirische Formel (Hill-System): C₂₆H₄₀O₈
• CAS-Nummer: 27215-14-1
• Molekulargewicht: 480.59
• MDL-Nummer: MFCD07779130
• UNSPSC-Code: 85151701
• PubChem Substanz-ID: 329757538
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Assay: ≥95% (HPLC)
• Haltbarkeit: limited shelf life, expiry date on the label
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): food and beverages
• Format: neat
• SMILES String: C[C@]1(CCC[C@@]2(C)[C@H](CCC3=CCOC3=O)C(=C)CC[C@H]12)CO[C@@H]4O[C@H](CO)[C@@H](O)[C@H](O)[C@H]4O
• InChI: 1S/C26H40O8/c1-15-5-8-19-25(2,14-33-24-22(30)21(29)20(28)18(13-27)34-24)10-4-11-26(19,3)17(15)7-6-16-9-12-32-23(16)31/h9,17-22,24,27-30H,1,4-8,10-14H2,2-3H3/t17-,18-,19-,20-,21+,22-,24-,25+,26+/m1/s1
• InChIKey: YGCYRQKJYWQXHG-RDNQFMDVSA-N

Beschreibung

Allgemeine Beschreibung

Neoandrographolide is a major diterpenoid isolated from Andrographis paniculata NEES (AP), a shrub belonging to the Acanthaceae family. It exhibits antihepatotoxic effect against carbon tetrachloride-induced hepatotoxicity. It also shows protective effects against galactosamine and paracetamol-induced intoxication in rats. It also helps in the suppression of human immunodeficiency virus type 1 (HIV)-induced cell cycle dysregulation and leads to a rise in CD4⁺ lymphocyte levels of HIV-1 infected individuals.

Anwendung

Neoandrographolide may be used as an analytical reference standard for the quantification of the analyte in the leaves of Andrographis paniculata using chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable