2011
Bilirubin
solid, bile pigment, Calbiochem®
Sinónimos:
Bilirubin
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Fórmula empírica (notación de Hill):
C33H36N4O6
Número CAS:
Peso molecular:
584.66
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
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Servicio técnico
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Permítanos ayudarleNombre del producto
Bilirubin, Principal pigment of bile and one of the major end products of hemoglobin decomposition.
Quality Level
description
RTECS - DU3038000
Merck USA index - 14, 1218
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze, protect from light
color
red-brown
solubility
chloroform: 1 mg/mL, alkaline solution: soluble
shipped in
ambient
storage temp.
10-30°C
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Este artículo | |||
|---|---|---|---|
| form solid | form powder | form - | form powder |
| Quality Level 100 | Quality Level 300 | Quality Level - | Quality Level 100 |
| manufacturer/tradename Calbiochem® | manufacturer/tradename - | manufacturer/tradename NIST® | manufacturer/tradename - |
| storage temp. 10-30°C | storage temp. −20°C | storage temp. −20°C | storage temp. - |
| storage condition OK to freeze, protect from light | storage condition - | storage condition - | storage condition - |
| solubility chloroform: 1 mg/mL, alkaline solution: soluble | solubility aqueous acid: soluble, aqueous base: soluble, benzene: soluble, chloroform: soluble | solubility - | solubility - |
General description
Bilirubin is an orange-yellow bile pigment[1] and one of the major end products of hemoglobin decomposition.[2] It contains conjugated double bonds and reactive hydrogen atoms. In adults, the upper limit of the normal range of bilirubin is >1mg/dL.[3] Serum levels of bilirubin in healthy newborns are less than 15 mg/dl.[4] This product corresponds to the unconjugated form.
Biochem/physiol Actions
Bilirubin is reported to cross the blood-brain barrier and exert significant antioxidant effects in the brain. This pigment aids in coloration in the various forms of jaundice.[1] Bilirubin levels act as biomarkers in liver and blood disorders.[5] Unconjugated form of bilirubin at lower levels serves as a physiological antioxidant.[2][5] However, increased concentration of bilirubin is toxic and leads to neonatal hyperbilirubinemia in neonates.[5]
Preparation Note
Unstable in basic solutions; reconstitute just prior to use.
Other Notes
Extinction coefficient (454 nm, CHCl3):59,100-62,300 M-1cm-1.
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary Target
Cell permeable: no
Reversible: no
Product does not compete with ATP.
Primary Target
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 2
flash_point_f
Not applicable
flash_point_c
Not applicable
Certificados de análisis (COA)
Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»
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What's in a name? Physiologic and pathologic jaundice: the conundrum of defining normal bilirubin levels in the newborn.
M Jeffrey Maisels
Pediatrics, 118(2), 805-807 (2006-08-03)
Elisabeth Lobner et al.
Frontiers in bioengineering and biotechnology, 8, 49-49 (2020-03-03)
The transmembrane protein CD19 is exclusively expressed on normal and malignant B cells and therefore constitutes the target of approved CAR-T cell-based cancer immunotherapies. Current efforts to assess CAR-T cell functionality in a quantitative fashion both in vitro and in
Zeng Hong et al.
ACS omega, 5(46), 29903-29912 (2020-12-01)
The reaction of magnesium or zinc amides with alkyl or benzyl halides is an attractive approach to make C-N bonds, especially for electron-poor organic halides. The magnesium-promoted preparation of hindered non-nucleophilic amine (N,N-diisopropylethylamine) from ethyl chloride and zinc diisopropylamide has
E Jiménez et al.
Environmental toxicology and pharmacology, 80, 103464-103464 (2020-08-05)
The identification of substances that prevent or minimize the detrimental effects of ionizing radiation is an essential undertaking. The aim of this paper was to evaluate and compare the radioprotective potential of chlorophyllin, protoporphyrin and bilirubin, with amifostine®, an US
Jürgen Reingruber et al.
The Journal of physiology, 598(17), 3747-3763 (2020-06-20)
Most vertebrate eyes have rods for dim-light vision and cones for brighter light and higher temporal sensitivity. Rods evolved from cone-like precursors through expression of different transduction genes or the same genes at different expression levels, but we do not
Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| GF31944416-1EA | 04061825459035 |
| GF20102465-5EA | 04061831012705 |
| GF73870476-2EA | 04061829966539 |
| GF78800452-5EA | 04061831018998 |
| GF31944416-2EA | 04061829971267 |
| GF20102465-2EA | 04061829962661 |
| GF20102465-1EA | 04061825430652 |
| GF73870476-1EA | 04061825442419 |
| GF73870476-5EA | 04061831018615 |
| GF78800452-2EA | 04061829967208 |
| GF78800452-1EA | 04061825451602 |
| T39853-250G | 04061837345258 |
| 33427-5ML-R | 04061826737927 |
| 8082649025 | 04027269053895 |
| 8082642500 | 04027269066840 |
| 89870-500ML | 04061838177445 |
| T39853-100G | 04061837345234 |
| T39853-5KG | 04061833613856 |
| 8082640100 | 04022536398815 |
| 8082640500 | 04022536398822 |
| 216836-1KG | 04061837506741 |
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