1370462

Losartan Potassium

United States Pharmacopeia (USP) Reference Standard

• Sinónimos: 2-Butyl-4-chloro-1-{[2′-(1H-tetrazol-5-yl)(1,1′-biphenyl)-4-yl]methyl}-1H-imidazole-5-methanol monopotassium salt
• Fórmula empírica (notación de Hill): C₂₂H₂₂ClKN₆O
• Número de CAS: 124750-99-8
• Peso molecular: 461.00
• Beilstein: 5845770
• Número MDL: MFCD02092704
• Código UNSPSC: 41116107
• ID de la sustancia en PubChem: 329750264
• NACRES: NA.24

Propiedades

• grado: pharmaceutical primary standard
• familia API: losartan
• fabricante / nombre comercial: USP
• aplicaciones: pharmaceutical (small molecule)
• Formato: neat
• cadena SMILES: CCCCc1nc(Cl)c(CO)n1Cc2ccc(cc2)-c3ccccc3-c4nnnn4[K]
• InChI: 1S/C22H22ClN6O.K/c1-2-3-8-20-24-21(23)19(14-30)29(20)13-15-9-11-16(12-10-15)17-6-4-5-7-18(17)22-25-27-28-26-22;/h4-7,9-12,30H,2-3,8,13-14H2,1H3;/q-1;+1
• Clave InChI: OXCMYAYHXIHQOA-UHFFFAOYSA-N
• Información sobre el gen: human ... AGTR1(185)

Descripción

Descripción general

Losartan potassium is a new drug used for hypertension. It is nonpeptide angiotensin II (AII) receptor antagonist.[1]

Losartan potassium is nonpeptide angiotensin II (AII) receptor antagonist and is orally active. It belongs to a new class of drugs introduced for clinical trials to treat hypertension.[1]

Aplicación

Losartan potassium USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Losartan Potassium and Hydrochlorothiazide Tablets
• Losartan Potassium Tablets

Acciones bioquímicas o fisiológicas

Losartan potassium is an orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist. Losartan potassium is used for treatment of hypertension.

orally available, potent, and selective competitive angiotensin II receptor type 1 (AT1) antagonist

Nota de análisis

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Otras notas

Sales restrictions may apply.

Información de seguridad

• Código de clase de almacenamiento: 11 - Combustible Solids
• Clase de riesgo para el agua (WGK): WGK 3
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable