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T3309

Transferrina human

≥98%

Sinónimos:

Siderofilina parcialmente saturada

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Tamaño de envaseSKUDisponibilidadPrecio
100 mg
Comprobar disponibilidad del carrito
$147.000
500 mg
Comprobar disponibilidad del carrito
$589.000
1 g
Comprobar disponibilidad del carrito
$807.000

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Número CAS:
UNSPSC Code:
12352202
EC Number:
234-318-8
NACRES:
NA.61
MDL number:
eCl@ss:
34058011
Form:
powder
Assay:
≥98%
Biological source:
human

$147.000


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biological source

human

Quality Segment

assay

≥98%

form

powder

Iron content

300-600 ppm

technique(s)

cell culture | stem cell: suitable

impurities

≤1.0 EU/mg endotoxin

UniProt accession no.

storage temp.

2-8°C

Gene Information

human ... TF(7018)

General description

Transferrin is an 80 kDa serum glycoprotein, which has an half-life of 8 to 10 days. The gene is located on human chromosome 3q22.1. Transferrin is expressed in hepatocytes.

Application

Transferrin has been used:
  • in isolation of epidermal stem cells and cell expansion[1]
  • to study the effect of compound treatment on transferrin uptake
  • for transferrin uptake and confocal imaging

Biochem/physiol Actions

Transferrin was shown to promote the proliferation of human lymphocytes. This effect is directly proportional to the level of iron present. [2]
Transferrin facilitates the transfer of iron to erythron and peripheral tissues. Mutations in this gene is associated with atransferrinemia. Transferrin is required for fetal development. It is non immunogenic and transferrin-conjugated drugs inhibits cardiotoxicity and drug resistance.

Analysis Note

Pureza por electroforesis en agarosa.

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

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Este artículo
T2252T5391T0665
technique(s)

cell culture | stem cell: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

technique(s)

cell culture | mammalian: suitable

assay

≥98%

assay

≥95% protein basis (biuret), ≥98% (agarose gel electrophoresis)

assay

≥98%

assay

≥97%

biological source

human

biological source

human

biological source

-

biological source

human plasma

form

powder

form

powder

form

powder

form

powder

UniProt accession no.

P02787

UniProt accession no.

P02787

UniProt accession no.

P02787

UniProt accession no.

P02787

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C


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WGK 3



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Contenido relacionado

Product Information Sheet






Número de artículo de comercio global

SKUGTIN
T3309-1G04061826694565
T3309-100MG04061837344183
T3309-500MG04061837344190

Questions

1–4 of 4 Questions  
  1. How long is this product (Transferrin human, T3309) stable upon reconstitution in water?

    1 answer
    1. When filter sterilized, aqueous solutions are expected to be stable at 4 °C for 5-10 days or in aliquots at -20°C for extended periods. Please see the link below to review additional information available in the product datasheet:
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/971/085/t3309pis.pdf

      Helpful?

  2. HOW IS THIS PROTEIN PRODUCED AND WHAT IS THE REST 2% IMPURITY? THANKS!

    1 answer
    1. This product is prepared by an ammonium sulfate precipitation process followed by a heat treatment and ion exchange chromatography purification. The specific details are considered proprietary. There is no treatment or handling during production that would be expected to cause deglycosylation of the protein. The residual impurities have not been identified. This product is tested for endotoxin and iron. Please see the Sample Certificates of Analysis: https://www.sigmaaldrich.com/certificates/Graphics/COfAInfo/fluka/pdf/PDF746107.pdf

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  4. What is the carbohydrate content of human transferrin?

    1 answer
    1. We have found the information on transferrin in a reference book:The Plasma Proteins, F.W. Putnam, ed, volume 2, chapter 4, Table II.According to the table, Transferrin is 6 percent carbohydrate, citing G.A. Jamieson, J. Biol. Chem. 240(7), 2914-2920 (1965).The table also gives information on the percentage of each type of monosaccharide that is present.

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