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Merck

S1764

Sigma-Aldrich

Complement sera human

lyophilized powder

Sinónimos:

Human Serum Complement

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1 ML
$95.000
5 X 1 ML
$342.000

$95.000


Fecha estimada de envío13 de mayo de 2025


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1 ML
$95.000
5 X 1 ML
$342.000

About This Item

Número MDL:
Código UNSPSC:
12352202
NACRES:
NA.61

$95.000


Fecha estimada de envío13 de mayo de 2025


Solicitar un pedido a granel

origen biológico

human

Nivel de calidad

Formulario

lyophilized powder

origen

USA origin

técnicas

cell culture | mammalian: suitable

impurezas

virus, tested

Condiciones de envío

dry ice

temp. de almacenamiento

−20°C

Descripción general

Complement serum is prepared from pooled human plasma and lyophilized from the amount of serum indicated on the label.

Aplicación

Complement sera human has been used:
  • to incubate DLD-1 or SW-620 cells to quantify C5a release
  • in multiplex bead antibody-binding assay to assay C3d
  • in complement-dependent cytotoxicity assay

Complement sera human has been used:
  • to incubate DLD-1 or SW-620 cells to quantify C5a release[1]
  • in multiplex bead antibody-binding assay to assay C3d[2]
  • in complement-dependent cytotoxicity assay[3]

The activity of complement sera can be determined by hemolytic assays in vitro. [4]

Forma física

Lyophilized powder from indicated amount of serum

Nota de análisis

Hemolytic titer (CH50 units per ml) is determined by method of Kabat and Mayer. Actual titer given on label.

Cláusula de descargo de responsabilidad

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable


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Savannah E Butler et al.
medRxiv : the preprint server for health sciences (2020-08-15)
Understanding humoral immune responses to SARS-CoV-2 infection will play a critical role in the development of vaccines and antibody-based interventions. We report systemic and mucosal antibody responses in convalescent individuals who experienced varying disease severity. Robust antibody responses to diverse
Helen Kotanides et al.
Cancer immunology research, 8(10), 1300-1310 (2020-09-03)
The programmed cell death protein 1 receptor (PD-1) and programmed death ligand 1 (PD-L1) coinhibitory pathway suppresses T-cell-mediated immunity. We hypothesized that cotargeting of PD-1 and PD-L1 with a bispecific antibody molecule could provide an alternative therapeutic approach, with enhanced
Savannah E Butler et al.
Frontiers in immunology, 11, 618685-618685 (2021-02-16)
Understanding humoral immune responses to SARS-CoV-2 infection will play a critical role in the development of vaccines and antibody-based interventions. We report systemic and mucosal antibody responses in convalescent individuals who experienced varying severity of disease. Whereas assessment of neutralization
S Nowicki et al.
Infection and immunity, 63(12), 4790-4794 (1995-12-01)
Human C1q displayed a dose-dependent protection of gonococcal cells (GC) from the bactericidal effect of newborn rat serum. All rat pups injected with C1q-preincubated GC developed bacteremia, while none of the animals injected with GC only were infected. After clearance
Yui Suzuki et al.
Clinical cancer research : an official journal of the American Association for Cancer Research, 25(14), 4388-4399 (2019-04-26)
The anti-CCR4 mAb, mogamulizumab, offers therapeutic benefit to patients with adult T-cell leukemia-lymphoma (ATL), but skin-related adverse events (AE) such as erythema multiforme occur frequently. The purpose of this study was to determine the mechanisms by which mogamulizumab causes skin-related

Questions

  1. Hello. This product is a pool of how many donnors ? Thanks for your help

    1 answer
    1. The donor pool size varies from lot to lot. Historical data indicates that the raw material is typically derived from a pool of 12 - 15 donors.

      Helpful?

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