Following reconstitution, this product is expected to be stable on ice or refrigerated for up to 8 hours, when used in coagulation studies. The stability of the prepared liquid, when stored at -20°C, has not been evaluated. However, various collection agencies report that fresh frozen plasma is stable for up to 1 year a -20°C. As a general rule, avoid repeated freeze thaw cycles. Note that some particulates may be present upon thawing frozen aliquots.
P9523
Plasma
from human
Sinónimos:
Citrated plasma
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| A ustedes/SKU | Disponibilidad | Precio |
|---|---|---|
1 mL | Comprobar disponibilidad del carrito | $31.900 |
5 mL | Comprobar disponibilidad del carrito | $110.000 |
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Servicio técnico
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Permítanos ayudarleQuality Segment
biological source
human
form
powder
contains
4% trisodium citrate as anticoagulant
impurities
HIV, hepatitis B and hepatitis C, none detected
storage temp.
2-8°C
General description
Plasma is the liquid part of the blood and lymphatic fluid, which makes up about half of its volume. Plasma is devoid of cells and, unlike serum, has not clotted. It is prepared from whole blood that is collected with anticoagulants (9:1) and centrifuged to remove cells and cellular debris. Some of the more common proteins found in plasma are albumin and prealbumin, α1-acid glycoprotein, transferrin, lipoproteins (HDL, LDL, and VLDL), immunoglobulins, complement proteins, and coagulation proteins (thrombin, plasminogin, and fibrinogen). Citrated plasma contains citrate (4% trisodium citrate) as an anticoagulant.
Plasma contains a variety of proteins with diverse functions. The primary functions of the plasma proteins include the maintenance of colloid osmotic pressure, pH, and electrolyte balance; the transport of metal ions, fatty acids, steroids, hormones, and drugs to various organs of the body; use as a source for amino acids for tissue nourishment; hemostasis and the prevention of thrombosis; the regulation of cellular activity and function through hormone signaling; and defense against invasion through the actions of antibodies and complement components.
Plasma contains a variety of proteins with diverse functions. The primary functions of the plasma proteins include the maintenance of colloid osmotic pressure, pH, and electrolyte balance; the transport of metal ions, fatty acids, steroids, hormones, and drugs to various organs of the body; use as a source for amino acids for tissue nourishment; hemostasis and the prevention of thrombosis; the regulation of cellular activity and function through hormone signaling; and defense against invasion through the actions of antibodies and complement components.
Preparation Note
Whole blood collected by standard industry method using citrate based anticoagulant. Whole blood is pooled and then centrifuged. The resulting plasma is 0.45 micron filtered and lyophilized from the indicated volumes.
Other Notes
This product is prepared from pooled human blood. It contains 4% trisodium citrate as an anticoagulant. It is tested for clotting, which indicates that the clotting factors in the product are active. However, it is not analyzed to determine whether other enzymes present are native or denatured.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
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Este artículo | |||
|---|---|---|---|
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level 300 |
| form powder | form powder | form powder | form powder |
| biological source human | biological source pig | biological source chicken | biological source bovine |
| impurities HIV, hepatitis B and hepatitis C, none detected | impurities - | impurities - | impurities - |
| contains 4% trisodium citrate as anticoagulant | contains 3.8% trisodium citrate as anticoagulant | contains 3.8% trisodium citrate as anticoagulant | contains 3.8% trisodium citrate as anticoagulant |
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Clase de almacenamiento
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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How should the product be stored after reconstitution?
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Is this plasma from a single donor or multiple donors?
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This product is prepared from pooled human blood, with each lot consisting of contributions from 1000-1500 healthy donors.
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Does this plasma contain C-reactive protein (CRP) biomarker? Does the product's quality remain consistent with each individual purchase?
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Whole blood is collected using a citrate-based anticoagulant, pooled, and then centrifuged. The resulting plasma is 0.45 micron filtered and lyophilized from the indicated volumes. This product is not tested for C-reactive protein. The Certificate of Analysis is available on this page to verify what this product is tested for, ensuring consistent quality.
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How should the dried plasma be reconstituted?
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The product can be reconstituted using either deionized water or 0.9% saline.
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How do you prepare the plasma? What solvent should be used and what solvent volume per 1ML-product?
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It is recommended to reconstitute this product in water to the volume stated on the label - either 1 mL or 5 mL.
See the link below for a sample Certificate of Analysis which includes solubility information:
https://www.sigmaaldrich.com/certificates/sapfs/PROD/sap/certificate_pdfs/COFA/Q14/P9523-1MLSLCP0492.pdfHelpful?
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The pack size for this product is mL. Is this the volume of lyophilized powder or the volume for reconstitution with H2O?
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The volume measurement refers to the starting volume of whole blood the plasma product was lyophilized from. Whole blood collected by standard industry method using citrate based anticoagulant. Whole blood is pooled and then centrifuged. The resulting plasma is 0.45 micron filtered and lyophilized from the indicated volumes.
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