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P4505

Protamine sulfate

powder

Sinónimos:

Clupeine

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Tamaño de envaseSKUDisponibilidadPrecio
1 g
Comprobar disponibilidad del carrito
$45.400
5 g
Comprobar disponibilidad del carrito
$115.000
25 g
Comprobar disponibilidad del carrito
$456.000

Acerca de este artículo

Número CAS:
UNSPSC Code:
12352202
NACRES:
NA.77
MDL number:

$45.400


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Nombre del producto

Protamine sulfate salt from herring, Grade III, histone, free(Millon test)

biological source

fish (herring)

Quality Level

type

Grade III

form

powder

impurities

histone, free (Millon test)

solubility

6 M HCl: 25 mg/mL, clear, colorless to very faintly yellow

Application

May be used for the removal of DNA from protein samples or for the purification of DNA binding proteins. It may be used as an alternative to polybrene in retroviral-mediated gene transfer.

Biochem/physiol Actions

Protamine in the form of solid lipid nanoparticles (SLN) promoted transfection with plasmid DNA more efficiently and with less cytotoxicity than comparable SLNs composed of Esterquat-1.
Protamine sulfate is a small cationic protein that binds and precipitates DNA. Neutralizes the anticoagulant activity of heparin. Inhibits lipoprotein lipase.

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Este artículo
P4380P4020P4005
biological source

fish (herring)

biological source

fish (salmon)

biological source

-

biological source

fish (salmon)

Quality Level

200

Quality Level

200

Quality Level

200

Quality Level

200

form

powder

form

powder

form

amorphous powder

form

solid

solubility

6 M HCl: 25 mg/mL, clear, colorless to very faintly yellow

solubility

6 M HCl: 25 mg/mL, clear, colorless to light yellow

solubility

6 M HCl: 25 mg/mL

solubility

H2O: soluble, clear to slightly hazy, colorless to faintly yellow

type

Grade III

type

Grade II

type

Grade X

type

Grade IV

impurities

histone, free (Millon test)

impurities

-

impurities

histone, free (Millon test)

impurities

Histone, free (Millon test)


Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)



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A Bonincontro et al.
Physics in medicine and biology, 34(5), 609-616 (1989-05-01)
The complex dielectric constant of arginine and protamine from herring sperm (clupeine) and their complexes with herring sperm DNA was measured at 10 GHz in the temperature range -20 to +45 degrees C by a microwave cavity perturbation method. The
Moyra Lawrence et al.
Science advances, 8(7), eabj8618-eabj8618 (2022-02-17)
Platelet deficiency, known as thrombocytopenia, can cause hemorrhage and is treated with platelet transfusions. We developed a system for the production of platelet precursor cells, megakaryocytes, from pluripotent stem cells. These cultures can be maintained for >100 days, implying culture
Lisanne T Laagland et al.
JOR spine, 5(3), e1219-e1219 (2022-10-08)
Repopulating the degenerated intervertebral disc (IVD) with tissue-specific nucleus pulposus cells (NPCs) has already been shown to promote regeneration in various species. Yet the applicability of NPCs as cell-based therapy has been hampered by the low cell numbers that can



Número de artículo de comercio global

SKUGTIN
P4505-5G04061832948461
P4505-25G04061832948454
P4505-1G04061834374664

Questions

  1. Is it possible to confirm whether product P4505 contains salts (Mg+2, Na+) as impurities or due to its origin?

    1 answer
    1. There is no information regarding the presence of other salts, as the product is currently sourced from an external supplier(s). The supplier's Certificate of Analysis does not mention the testing for salts such as magnesium or calcium.

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