C4835
Carcinoembryonic Antigen human
≥95% (SDS-PAGE), buffered aqueous solution
Sinónimos:
Cancer-associated CEA
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| Tamaño de envase | SKU | Disponibilidad | Precio |
|---|---|---|---|
| 25 μg | Comprobar disponibilidad del carrito | $243.000 |
Acerca de este artículo
$243.000
Comprobar disponibilidad del carrito
Servicio técnico
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Permítanos ayudarleQuality Segment
assay
≥95% (SDS-PAGE)
form
buffered aqueous solution
UniProt accession no.
shipped in
dry ice
storage temp.
−20°C
Gene Information
human ... CEACAM5(1048)
General description
Carcinoembryonic antigen(CEA) or CEA cell adhesion molecule 5 (CEACAM5), is encoded by the gene mapped to human chromosome 19q13.2.[1] CEACAM5 is a member of the CEACAM family. This glycosylated protein contains a typical N-terminal variable immunoglobulin (Ig)-like domain, constant Ig-like domain, and a hydrophobic transmembrane domain with a glycosylphosphatidylinositol lipid moiety.[2]
Application
Biochem/physiol Actions
Carcinoembryonic antigen cell adhesion molecule 5 (CEACAM5) aids in cell adhesion and migration. In addition, this protein inhibits anoikis and thereby promoting tumorigenesis and metastasis. CEACAM5 is used as a biomarker to detect new cancer and cancer recurrence, particularly those with colorectal cancer. Upregulated expression of the gene enhances non-small-cell lung cancer (NSCLC) cell proliferation and invasion by regulating p38–Smad2/3 signaling. Therefore, CEACAM5 might be considered as an effective therapeutic target for treating NSCLC. Overexpression of the gene has also been observed in various types of cancer including gastrointestinal, pancreatic, and breast cancers.[2]
Packaging
Package size based on protein content
Physical form
Solution in 0.15 M phosphate buffered saline, pH 7.4, containing 0.1% sodium azide.
Analysis Note
Highly purified
1 of 1
Este artículo | |||
|---|---|---|---|
| assay ≥95% (SDS-PAGE) | assay ≥70% (SDS-PAGE) | assay - | assay ≥92% (SDS-PAGE) |
| Quality Level 200 | Quality Level 200 | Quality Level 200 | Quality Level - |
| form buffered aqueous solution | form buffered aqueous glycerol solution | form - | form lyophilized powder |
| shipped in dry ice | shipped in dry ice | shipped in dry ice | shipped in wet ice |
| Gene Information human ... CEACAM5(1048) | Gene Information human ... FLT3(2322) | Gene Information human ... CEACAM5(1048) | Gene Information human ... MMP-2(4313) |
| UniProt accession no. | UniProt accession no. | UniProt accession no. | UniProt accession no. |
flash_point_f
Not applicable
flash_point_c
Not applicable
Clase de almacenamiento
12 - Non Combustible Liquids
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Número de artículo de comercio global
| SKU | GTIN |
|---|---|
| C4835-25UG | 04061833493120 |