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C1013

Carrageenan

suitable for gel preparation

Sinónimos:

Vegetable gelatin

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Número CAS:
9000-07-1
UNSPSC Code:
12352201
EC Number:
232-524-2
NACRES:
NA.25
MDL number:
MFCD00081480
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biological source

algae (red)

Quality Level

200

description

Predominantly κ and lesser amounts of λ carrageenan

form

powder

color

white to light brown

useful pH range

7.5-10.5 (1.5% in water)

cation traces

Ca: <3.5%, K: <11%, Na: <2.0%

suitability

suitable for gel preparation

storage temp.

room temp

General description

Carrageenans are mucopolysaccharides from the cell walls of the red algae. They are anionic linear polymers composed of 1,3α-1,4β-galactans having one (κ-), two (ι-) or three (λ-) sulfates per disaccharide unit. In ionic solutions, κ- and ι-carrageenans self-associate into helical structures that form rigid or flexible gels, respectively. λ-carrageenans do not form helices and are non-gelling. Carrageenans are used commercially as thickeners and stabilizing agents.

Application

Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages. As ι-, κ-, and λ-carrageenans have varying degress of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.
Carrageenans are used to suppress immune response in vivo and in vitro via mechanisms believed to involve selective cytopathic effect on macrophages.[1] As ι-, κ-, and λ- carrageenans have varying degrees of sulfation, they may be studied comparatively for differences in protective, antiviral, and immunosuppression activities.[1] Carrageenan may be used in the development of biomaterials such as bone graft substitutes; entrapping vessels such as biobeads and encapsulation vehicles for drug delivery. Carrageenan be used to develop hydrogels.[2]

Preparation Note

Blended from various seaweeds to produce rigid gels.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

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Este artículo
C113822048A4550
Carrageenan suitable for gel preparation

Sigma-Aldrich

C1013

Carrageenan

&#953;-Carrageenan Predominantly iota carrageenan

Sigma-Aldrich

C1138

ι-Carrageenan

&#954;-Carrageenan sulfated plant polysaccharide

Sigma-Aldrich

22048

κ-Carrageenan

Agar Type A, suitable for plant cell culture

Sigma-Aldrich

A4550

Agar

biological source

algae (red)

biological source

algae (Eucheuma spinosum)

biological source

plant

biological source

algae (Rhodophyceae)

Quality Level

200

Quality Level

200

Quality Level

100

Quality Level

200

form

powder

form

powder

form

powder

form

powder

suitability

suitable for gel preparation

suitability

-

suitability

-

suitability

-

storage temp.

room temp

storage temp.

room temp

storage temp.

-

storage temp.

room temp

useful pH range

7.5-10.5 (1.5% in water)

useful pH range

8.0 - 10.5

useful pH range

-

useful pH range

-

Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

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Certificados de análisis (COA)

Lot/Batch Number
0000537856
0000537854
0000537855
0000537853
0000479242

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Artículos

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Discover the role of carbohydrates in drug delivery, from solubility and stability improvement to advanced controlled-release systems.

Ahu Uraz et al.
Journal of clinical and experimental dentistry, 5(1), e23-e29 (2014-01-24)
The objective of this study was to histologically and histomorphometrically evaluate the efficacy of the new formulations of eggshell-derived calcium carbonate in rats. The study was conducted on 30 adult male rats. Four standardized and circular intrabony defects were created
José A Fernández-Romero et al.
Antimicrobial agents and chemotherapy, 56(1), 358-368 (2011-11-09)
Topical microbicides that block the sexual transmission of HIV and herpes simplex virus 2 (HSV-2) are desperately needed to reduce the incidence of HIV infections worldwide. Previously we completed phase 3 testing of the carrageenan-based gel Carraguard. Although the trial
A W Thomson
Biomedicine / [publiee pour l'A.A.I.C.I.G.], 28(3), 148-152 (1978-05-01)
Since the biological effects of carrageenan were reviewed in 1972 by Di Rosa it has become clear from a large number of reports that this algal polysaccharide markedly influences immune responses. Profound suppression of immunity evidenced by impaired antibody production
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Número de artículo de comercio global

SKUGTIN
C1013-100G04061833460283
C1013-25G04061833460306
C1013-500G04061833460313
C1013-1KG04061833460290

Questions

1–5 of 5 Questions  

  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

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  2. Can this Carageenan be used for research purpose for induction of arthritis in rats?

    1 answer

    1. This product is intended for the synthesis of substances and is not intended for direct use in humans or animals.

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  3. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer

    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  4. What is the average molecular weight?

    1 answer

    1. The molecular weight of this product is not determined. Historical data indicate that this material is comprised primarily of the kappa form. In general, Carrageenans have a number average molecular weight range of 193 kDa to 324 kDa with an average molecular weights range of 453 kDa to 652 kDa. Please see the link below for additional information:
      https://pubmed.ncbi.nlm.nih.gov/11552743/

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  5. Is this carrageenan a mixture of kapa and lamda?

    1 answer

    1. Per the properties section, Product C1013 is a mixture of predominantly κ (kappa) and lesser amounts of λ (lambda) carrageenan.

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