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A6428

Aflatoxin M₁

Name: Aflatoxin M<SUB>1</SUB>
Brand: SIGMA
Price: 147000 CLP

From Aspergillus flavus, , mycotoxin, film

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Tamaño de envase	Disponibilidad	Precio
5 μg	Comprobar disponibilidad del carrito	$147.000
10 μg	Comprobar disponibilidad del carrito	$222.000
50 μg	Comprobar disponibilidad del carrito	$756.000
250 μg	Comprobar disponibilidad del carrito	$2.610.000

Acerca de este artículo

Fórmula empírica (notación de Hill):

C₁₇H₁₂O₇

Número CAS:

6795-23-9

Peso molecular:

328.27

NACRES:

NA.77

PubChem Substance ID:

24891088

UNSPSC Code:

12352200

EC Number:

229-865-4

MDL number:

MFCD00871812

Form:

film

Quality level:

200

$147.000

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Propiedades

Nombre del producto

Aflatoxin M₁, from Aspergillus flavus

biological source

Aspergillus flavus

Quality Level

200

form

film

storage temp.

2-8°C

SMILES string

[H][C@]12OC=C[C@@]1(O)c3c(O2)cc(OC)c4C5=C(C(=O)CC5)C(=O)Oc34

InChI

1S/C17H12O7/c1-21-9-6-10-13(17(20)4-5-22-16(17)23-10)14-12(9)7-2-3-8(18)11(7)15(19)24-14/h4-6,16,20H,2-3H2,1H3/t16-,17-/m1/s1

InChI key

MJBWDEQAUQTVKK-IAGOWNOFSA-N

Descripción

General description

Aflatoxins are metabolites of fungus, that are mainly seen in feeds and foods. Aflatoxin M₁ is a hydroxylated metabolite of aflatoxin B₁. It is liberated in milk, urine and produced in liver after receiving aflatoxin B₁.

Application

Aflatoxin M1 is both a hepatotoxic and hepatocarcinogenic mycotoxin that has been shown to cause immunosuppression in animals.

Aflatoxin M1 has been used as a standard to investigate the incidence and occurrence of aflatoxin M₁ (AFM₁) in Brazilian milk and infant formula. It has also been used as standard to investigate the incidence and occurrence of aflatoxin M1 (AFM₁) in dairy products produced in Brazil.

Biochem/physiol Actions

Aflatoxin M1 possesses hepatocarcinogenic properties.

Preparation Note

Aspergillus flavus metabolite.

Disclaimer

Possibly carcinogenic.

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1 of 1

Este artículo	A6655	A0138	A9441
Sigma-Aldrich A6428 Aflatoxin M₁	Sigma-Aldrich A6655 Aflatoxin B₁−BSA Conjugate from Aspergillus flavus	Sigma-Aldrich A0138 Aflatoxin G₁	Sigma-Aldrich A9441 Aflatoxin B + G mixture
form film	form powder	form powder	form dry concentrate
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200
storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. 2-8°C
biological source Aspergillus flavus	biological source -	biological source Aspergillus flavus	biological source -

pictograms

GHS06,GHS08

signalword

Danger

hcodes

H300 + H310 + H330,H340,H350

pcodes

P202 - P260 - P264 - P280 - P302 + P352 + P310 - P304 + P340 + P310

Hazard Classifications

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Carc. 1B - Muta. 1B

Clase de almacenamiento

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Artículos

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete.

Development of an electrochemical biosensor for the detection of aflatoxin M1 in milk.

Nathalie Paniel et al.

Sensors (Basel, Switzerland), 10(10), 9439-9448 (2010-01-01)

We have developed an electrochemical immunosensor for the detection of ultratrace amounts of aflatoxin M(1) (AFM(1)) in food products. The sensor was based on a competitive immunoassay using horseradish peroxidase (HRP) as a tag. Magnetic nanoparticles coated with antibody (anti-AFM(1))

Aflatoxins

Handbook of Secondary Fungal Metabolites, 545-569 (2003)

Occurrence of aflatoxin M1 in dairy products in Brazil

Iha MH, et al.

Food Control, 22(12), 1971-1974 (2011)

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Número de artículo de comercio global

SKU	GTIN
A6428-250UG	04061832938837
A6428-10UG	04061833382257
A6428-50UG	04061835381128
A6428-5UG	04061833382264

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