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04471

(R)-(+)-α-Lipoic acid

analytical standard

Sinónimos:

(R)-(+)-1,2-Dithiolane-3-pentanoic acid, (R)-6,8-Dithiooctanoic acid, (R)-6,8-Thioctic acid

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Tamaño de envaseSKUDisponibilidadPrecio
100 mg
Comprobar disponibilidad del carrito
$188.000

Acerca de este artículo

Fórmula empírica (notación de Hill):
C8H14O2S2
Número CAS:
Peso molecular:
206.33
NACRES:
NA.24
PubChem Substance ID:
UNSPSC Code:
85151701
MDL number:

$188.000


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grade

analytical standard

Quality Segment

assay

≥98.0% (HPLC)

optical activity

[α]/D +115±5°, c = 1% in ethanol

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

mp

48-52 °C (lit.)

application(s)

cleaning products
cosmetics
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

OC(=O)CCCC[C@@H]1CCSS1

InChI

1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)/t7-/m1/s1

InChI key

AGBQKNBQESQNJD-SSDOTTSWSA-N

General description

α-Lipoic acid is an antioxidant which is generally present in plants, animals and many other microorganisms.

Application

α-Lipoic acid has been used as a reference standard for the analysis of α-lipoic acid in human plasma by high performance liquid chromatography coupled to electron capture detector (HPLC-ECD), in various food matrices and dietary supplements[1] by HPLC combined with coulometric electrode array detector (CEAD) as well as electrospray ionization mass spectrometer (ESI-MS).
It may be used as a reference standard for the determination of α-lipoic acid in human urine by isocratic reversed-phase HPLC and in α-lipoic acid capsules by HPLC with chemiluminescence detection.

Packaging

Bottomless glass bottle. Contents are inside inserted fused cone.

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Este artículo
07039085611368201
application(s)

cleaning products
cosmetics
food and beverages
personal care

application(s)

-

application(s)

-

application(s)

pharmaceutical (small molecule)

technique(s)

HPLC: suitable, gas chromatography (GC): suitable

technique(s)

-

technique(s)

-

technique(s)

-

format

neat

format

-

format

-

format

neat

Quality Level

100

Quality Level

100

Quality Level

100, 200

Quality Level

-

grade

analytical standard

grade

-

grade

-

grade

pharmaceutical primary standard

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

2-8°C


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Clase de almacenamiento

11 - Combustible Solids

wgk

WGK 3



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Determination of lipoic acid in human plasma by HPLC-ECD using liquid-liquid and solid-phase extraction: Method development, validation and optimization of experimental parameters.
Khan, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences, 878(28), 2782-2788 (2010)
W Witt et al.
Journal of chromatography. B, Biomedical sciences and applications, 705(1), 127-131 (1998-03-14)
A new method for the quantitation of lipoic acid in plasma and tissues based on the selective precolumn derivatization of thiols with the fluorescent label monobromobimane is described. After extraction with diethyl ether, the dithiolane ring of lipoic acid is
Determination of lipoic acid by flow-injection and high-performance liquid chromatography with chemiluminescence detection.
Wolyniec, et al.
Talanta, 96(2), 223-229 (2012)



Número de artículo de comercio global

SKUGTIN
PHR1916-3X1.2ML04061835220847
H41544-25ML04061833794739
H41544-4L04061833794746
804512100004022536385044
804512602504022536622002
804512010004022536385037
804512250004022536385051
78891-1ML04061832947495
H41544-500ML04061833794753
78891-5ML04061837242427
04471-100MG04061838630667

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