1.00574

NMP

for Peptide Synthesis

• Sinónimos: 1-Methyl-2-pyrrolidone, NMP, N-Methyl-2-pyrrolidone
• Fórmula empírica (notación de Hill): C₅H₉NO
• Número de CAS: 872-50-4
• Peso molecular: 99.13
• MDL number: MFCD00003193
• UNSPSC Code: 12352115
• EC Index Number: 212-828-1
• NACRES: NA.22

Propiedades

• product name: 1-Methyl-2-pyrrolidone, for Peptide Synthesis
• vapor pressure: 0.32 hPa ( 20 °C)
• Quality Level: 200
• assay: ≥99.7% (GC)
• form: liquid
• autoignition temp.: 245 °C
• potency: 3598 mg/kg LD₅₀, oral (Rat); 8000 mg/kg LD₅₀, skin (Rabbit)
• expl. lim.: 1.3-9.5 % (v/v)
• pH: 8.5-10.0 (20 °C, 100 g/L in H₂O)
• bp: 202 °C/1013 hPa
• mp: -24 °C
• transition temp: flash point 91 °C
• density: 1.03 g/cm³ at 20 °C
• application(s): peptide synthesis
• storage temp.: 2-30°C
• InChI: 1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3
• InChI key: SECXISVLQFMRJM-UHFFFAOYSA-N

Descripción

General description

N-methyl-2-pyrrolidone (NMP) is an organic solvent that finds applications in numerous industries, including petrochemicals, plastics, microelectronics, and to produce pigments, cosmetics, and drugs. It is commonly used worldwide as an organic solvent, intermediate, or surfactant in various industrial and consumer applications. The unique characteristics of NMP, including its ability to mix with water and organic solvents, and its temperature, polarity, and composition stability, make it a solvent of great interest in extractive distillation.

Application

1-Methyl-2-pyrrolidone can be used as a solvent during the peptide bond formation reactions.

Información de seguridad

• pictograms: GHS07,GHS08
• signalword: Danger
• hcodes: H315 - H319 - H335 - H360D
• pcodes: P202 - P261 - P264 - P302 + P352 - P305 + P351 + P338 - P308 + P313
• Hazard Classifications: Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 1
• flash_point_f: 195.8 °F - Pensky-Martens closed cup
• flash_point_c: 91 °C - Pensky-Martens closed cup